Art

J-GLOBAL ID：200902268468719589   Reference number：07A0819649

Production of Recombinant β-Hexosaminidase A, a Potential Enzyme for Replacement Therapy for Tay-Sachs and Sandhoff Diseases, in the Methylotrophic Yeast Ogataea minuta

メチロトローフ酵母Ogataea minutaにおけるTay-Sachs病及びSandhoff病の置換療法の可能性酵素,組換体β-ヘキソサミニダーゼAの生産

Author (21)： AKEBOSHI Hiromi (National Inst. of Advanced Industrial Sci. and Technol., Tsukuba, JPN) ,  AKEBOSHI Hiromi (JST-CREST, Kawaguchi, JPN) ,  CHIBA Yasunori (National Inst. of Advanced Industrial Sci. and Technol., Tsukuba, JPN) ,  CHIBA Yasunori (JST-CREST, Kawaguchi, JPN) ,  KASAHARA Yoshiko (National Inst. of Advanced Industrial Sci. and Technol., Tsukuba, JPN) ,  TAKASHIBA Minako (National Inst. of Advanced Industrial Sci. and Technol., Tsukuba, JPN) ,  TAKAOKA Yuki (National Inst. of Advanced Industrial Sci. and Technol., Tsukuba, JPN) ,  OHSAWA Mai (JST-CREST, Kawaguchi, JPN) ,  OHSAWA Mai (Tokyo Metropolitan Inst. of Medical Sci., Tokyo, JPN) ,  TAJIMA Youichi (JST-CREST, Kawaguchi, JPN) ,  TAJIMA Youichi (Tokyo Metropolitan Inst. of Medical Sci., Tokyo, JPN) ,  KAWASHIMA Ikuo (JST-CREST, Kawaguchi, JPN) ,  KAWASHIMA Ikuo (Tokyo Metropolitan Inst. of Medical Sci., Tokyo, JPN) ,  TSUJI Daisuke (JST-CREST, Kawaguchi, JPN) ,  TSUJI Daisuke (Univ. Tokushima, Tokushima, JPN) ,  ITOH Kohji (JST-CREST, Kawaguchi, JPN) ,  ITOH Kohji (Univ. Tokushima, Tokushima, JPN) ,  SAKURABA Hitoshi (JST-CREST, Kawaguchi, JPN) ,  SAKURABA Hitoshi (Tokyo Metropolitan Inst. of Medical Sci., Tokyo, JPN) ,  JIGAMI Yoshifumi (National Inst. of Advanced Industrial Sci. and Technol., Tsukuba, JPN) ,  JIGAMI Yoshifumi (JST-CREST, Kawaguchi, JPN)
Material： Applied and Environmental Microbiology  (Appl Environ Microbiol)
Volume： 73  Issue： 15  Page： 4805-4812  Publication year： Aug. 2007 
JST Material Number： A0427A  ISSN： 0099-2240  CODEN： AEMIDF  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *methylotroph ,...
Semi thesaurus term： Sandhoff Disease ,...

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JST classification (2)： Basic research of enzyme preparations and enzyme inhibitor preparations  (GW21010W) ,  Microbial enzyme production  (FK03030L)

Terms in the title (8)： メチロトローフ酵母 ,  Tay-Sachs病 ,  Sandhoff病 ,  置換療法 ,  可能性 ,  酵素 ,  組換体 ,  ヘキソサミニダーゼA