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J-GLOBAL ID：200902268511871012   Reference number：05A0481371

Aerobic and Anaerobic Biotransformation of Bile Acids by Escherichia coli (II): No Conversion of α-Muricholic Acid by 7α-Hydroxysteroid Dehydrogenase of E. coli

Escherichia coliによる胆汁酸の好気的および嫌気的生物変換(II): E.coliの7α-ヒドロキシステロイドデヒドロゲナーゼによるα-ムリコール酸の無変換

Author (7)： OGURA Yoshio (Tottori Univ., Yonago, JPN) ,  YAMAGA Nobuo (Tottori Univ., Yonago, JPN) ,  SUZUKI Takao (Tottori Univ., Yonago, JPN) ,  KIMURA Koji (Tottori Univ., Yonago, JPN) ,  KIDO Yasuhiro (Kyoto Prefectural Univ., Kyoto, JPN) ,  YAMADA Kazuo (Tottori Univ., Yonago, JPN) ,  UCHIDA Kiyohisa (Tottori Univ., Yonago, JPN)
Material： Bioscience and Microflora  (Biosci Microflora)
Volume： 24  Issue： 2  Page： 41-44  Publication year： Apr. 2005 
JST Material Number： X0537A  ISSN： 1342-1441  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Escherichia coli ,...

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JST classification (1)： Metabolism and nutrition  (EG03054K)

Substance index (5)： α-Muricholic acid ,  β-Muricholic acid ,  Chenodeoxycholic acid ,  Hyocholic acid ,  Ursocholic acid

Reference (15)：

• (1) Aries V, Hill MJ. 1970. Degradation of steroids by intestinal bacteria. II. Enzymes catalyzing the oxidoreduction of the 3α-, 7α- and 12α-hydroxyl groups in cholic acid, and the dehydroxylation of the 7-hydroxyl group. Biochim Biophys Acta 202: 535-543.
• (2) Arimoto K, Adachi K, Yamaga N. 1982. 7β,12β-Dihydroxy-5 β-cholan-24-oic acid as an internal standard for quantitative determination of bile acids by gas chromatography. Steroids 39: 631-641.
• (3) Haslewood ES, Haslewood GAD. 1976. The specificity of a 7α-hydroxy steroid dehydrogenase from Escherichi coli. Biochem J 157: 207-210.
• (4) Iida T, Momose T, Tamura T, Matsumoto T, Chang FC, Goto J, Nambara T. 1989. Potential bile acid metabolites. 14. Hyocholic and muricholic acid stereoisomers. J Lipid Res 30: 1266-1279.
• (5) Imamura T, Sakamoto N, Tamaki M, Hirano S. 1979. Transformation of bile acids by members of the Enterobacteriaceae. Jpn J Bacteriol 34: 513-520.

Terms in the title (7)： Escherichia ,  胆汁酸 ,  好気 ,  嫌気 ,  生物変換 ,  ヒドロキシステロイドデヒドロゲナーゼ ,  α-ムリコール酸