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J-GLOBAL ID：200902268879466878   Reference number：06A0465766

Gene expression analysis using human cancer xenografts to identify novel predictive marker genes for the efficacy of 5-fluorouracil-based drugs

5-フルオロウラシルをベースとする薬剤効果の新規予測マーカー遺伝子同定のためのヒト癌異種移植片による遺伝子発現分析

Author (9)： OOYAMA Akio (Taiho Pharmaceutical Co., Tokushima, JPN) ,  TAKECHI Teiji (Taiho Pharmaceutical Co., Tokushima, JPN) ,  TODA Etsuko (Taiho Pharmaceutical Co., Tokushima, JPN) ,  NAGASE Hideki (Taiho Pharmaceutical Co., Tokushima, JPN) ,  OKAYAMA Yoshihiro (Taiho Pharmaceutical Co., Tokushima, JPN) ,  KITAZATO Kenji (Taiho Pharmaceutical Co., Tokushima, JPN) ,  SUGIMOTO Yoshikazu (Taiho Pharmaceutical Co., Tokushima, JPN) ,  OKA Toshinori (Taiho Pharmaceutical Co., Tokushima, JPN) ,  FUKUSHIMA Masakazu (Taiho Pharmaceutical Co., Tokushima, JPN)
Material： Cancer Science  (Cancer Sci)
Volume： 97  Issue： 6  Page： 510-522  Publication year： Jun. 2006 
JST Material Number： W1423A  ISSN： 1347-9032  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： *drug sensitivity ,...
Semi thesaurus term： cisplatin ,...

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JST classification (1)： Clinical oncology in general  (GE03010Y)

Substance index (6)： 5'-DFUR ,  CPT-11 ,  TS-1 ,  UFT ,  Capecitabine ,  Paclitaxel

Reference (50)：

• GOLUB, TR. Molecular classification of cancer : class discovery and class prediction by gene expression monitoring. Science. 1999, 286, 531-537
• GOLUB, TR. Genome-wide views of cancer. N Engl J Med. 2001, 8, 601-602
• ULRICH, CM. Cancer pharmacogenetics : polymorphisms, pathways and beyond. Nat Rev Cancer. 2003, 12, 912-920
• MAYER, F. A phase I study of oral uracil-ftorafur plus folinic acid in combination with weekly paclitaxel in patients with solid tumors. Ann Oncol. 2002, 5, 755-759
• TAKAHASHI, N. Third-line chemotherapy with paclitaxel, irinotecan hydrochloride and cisplatin for recurrent gastric cancer : a case report. Hepatogastroenterology. 2005, 61, 326-328

Terms in the title (9)： 5-フルオロウラシル ,  薬剤効果 ,  予測マーカー ,  遺伝子同定 ,  ヒト ,  癌 ,  異種移植片 ,  遺伝子発現 ,  分析