Art

J-GLOBAL ID：200902269313434410   Reference number：09A0180613

The Absolute Configuration of the (+)- and (-)-cis- and (+)- and (-)-trans-1-Benzyl-4-hydroxypiperidine-3-methanols: An Unusual Application of the ¹H-NMR-Mosher Method

(+)-及び(-)-cis-並びに(+)-及び(-)-trans-1-ベンジル-4-ヒドロキシピペリジン-3-メタノールの絶対配置 ¹H-NMR-Mosher法の珍しい応用

Author (3)： CLERC Christian (Univ. Zuerich, Zuerich) ,  MATARAZZO Igor (Univ. Zuerich, Zuerich) ,  RUEEDI Peter (Univ. Zuerich, Zuerich)
Material： Helvetica Chimica Acta  (Helv Chim Acta)
Volume： 92  Issue： 1  Page： 14-28  Publication year： Jan. 20, 2009 
JST Material Number： C0113A  ISSN： 0018-019X  CODEN： HCACAV  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *absolute configuration ,  *nitrogen heterocyclic compound ,  enantiomer ,  crystal structure ,  baker's yeast ,  reduction (reaction) ,  diastereomer ,  Hydrolysis ,  asymmetric synthesis ,  derivatization ,  *Piperidines ,  microorganism
Semi thesaurus term： Mosher法

JST classification (2)： Pyridines  (CF07095Q) ,  Configuration and conformation of molecules  (BH05022J)

Substance index (18)： Mosher’s acid ,  4-Oxopiperidine-3-carboxylic acid ethyl ester ,  4-Oxo-3-piperidinecarboxylic acid methyl ester ,  (3R)-1-Benzyl-3α-(hydroxymethyl)piperidine-4β-ol ,  (3R,4S)-1-Benzyl-3-[[(2R)-2-phenyl-2-methoxy-3,3,3-trifluoropropionyl]oxymethyl]-4-[[(2R)-2-phenyl-2-methoxy-3,3,3-trifluoropropionyl]oxy]piperidine ,  (3R,4S)-1-Benzyl-3-[[(2S)-2-phenyl-2-methoxy-3,3,3-trifluoropropionyl]oxymethyl]-4-[[(2S)-2-phenyl-2-methoxy-3,3,3-trifluoropropionyl]oxy]piperidine ,  (3S)-1-Benzyl-3β-(hydroxymethyl)piperidine-4β-ol ,  (3S,4S)-1-Benzyl-3-[[(2R)-2-phenyl-2-methoxy-3,3,3-trifluoropropionyl]oxymethyl]-4-[[(2R)-2-phenyl-2-methoxy-3,3,3-trifluoropropionyl]oxy]piperidine ,  (3S,4S)-1-Benzyl-3-[[(2S)-2-phenyl-2-methoxy-3,3,3-trifluoropropionyl]oxymethyl]-4-[[(2S)-2-phenyl-2-methoxy-3,3,3-trifluoropropionyl]oxy]piperidine ,  (3S)-1-Benzyl-3β-(hydroxymethyl)piperidine-4α-ol ,  (3S,4R)-1-Benzyl-3-[[(2R)-2-phenyl-2-methoxy-3,3,3-trifluoropropionyl]oxymethyl]-4-[[(2R)-2-phenyl-2-methoxy-3,3,3-trifluoropropionyl]oxy]piperidine ,  (3S,4R)-1-Benzyl-3-[[(2S)-2-phenyl-2-methoxy-3,3,3-trifluoropropionyl]oxymethyl]-4-[[(2S)-2-phenyl-2-methoxy-3,3,3-trifluoropropionyl]oxy]piperidine ,  (3R)-1-Benzyl-3α-(hydroxymethyl)piperidine-4α-ol ,  (3R,4R)-1-Benzyl-3-[[(2R)-2-phenyl-2-methoxy-3,3,3-trifluoropropionyl]oxymethyl]-4-[[(2R)-2-phenyl-2-methoxy-3,3,3-trifluoropropionyl]oxy]piperidine ,  (3R,4R)-1-Benzyl-3-[[(2S)-2-phenyl-2-methoxy-3,3,3-trifluoropropionyl]oxymethyl]-4-[[(2S)-2-phenyl-2-methoxy-3,3,3-trifluoropropionyl]oxy]piperidine ,  (3S,4S)-1-Benzyl-4-hydroxypiperidine-3-carboxylic acid methyl ester ,  (4aR,8aS)-2,2-Dimethyl-6-benzyl-4a,5,6,7,8,8a-hexahydro-4H-1,3-dioxino[5,4-c]pyridine ,  (4aS,8aS)-2,2-Dimethyl-6-benzyl-4a,5,6,7,8,8a-hexahydro-4H-1,3-dioxino[5,4-c]pyridine

Terms in the title (5)： CIS ,  ベンジル ,  メタノール ,  1H-NMR ,  応用