Art

J-GLOBAL ID：200902269336809682   Reference number：08A0559218

糖尿病血管合併症における酸化ストレスの役割

Author (2)： INOGUCHI TOYOSHI (九大 大学院医学系研究院 臨床医学部門 内科 病態制御内科学分野) ,  TAKAYANAGI RYOICHI (九大 大学院医学系研究院 臨床医学部門 内科 病態制御内科学分野)
Material： 福岡医学雑誌  (Fukuoka Acta Medica)
Volume： 99  Issue： 3  Page： 47-55  Publication year： Mar. 25, 2008 
JST Material Number： F0687A  ISSN： 0016-254X  CODEN： FKIZA4  Document type： Article
Article type： 文献レビュー  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *diabetic angiopathy ,...
Semi thesaurus term： 生体内活性酸素種 ,...

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JST classification (1)： Metabolic diseases,nutritional diseases in general.  (GD05010J)

Substance index (2)： 8-Hydroxy-2'-deoxyguanosine ,  Pitavastatin

Reference (33)：

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• Sheets MJ and King GL: Molecular understanding of hyperglycemia’s adverse effects for diabetic vascular complications. JAMA 288: 2579-2588, 2002.
• Nishikawa T, Edelstein D, Du XL, Yamagishi S, Matsumura T, Kaneda Y, Yorek MA, Beebe D, Oates PJ, Hammes HP, Giardino I and Brownlee M: Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage. Nature 404: 787-790, 2000.
• Inoguchi T, Li P, Umeda F, Kakimoto M, Imamura M, Aoki T, Etoh T, Hashimoto T, Naruse M, Sano T, Utsumi H and Nawata H: High glucose level and free fatty acid stimulate reactive oxgen species production through protein kinase C-dependent activation of NAD (P) H oxidase in cultured vascular cells. Diabetes 49: 1939-1945, 2000.
• Tsubouchi H, Inoguchi T, Sonta T, Sato N, Sekiguchi N, Kobayashi K, Sumimoto H, Utsumi H and Nawata H: Statin attenuates high glucose-induced and diabetes-induced oxidative stress in vitro and in vivo evaluated by electron spin resonance measurement. Free Radic. Biol. Med.39: 444-452, 2005.

Terms in the title (3)： 糖尿病血管合併症 ,  酸化ストレス ,  役割