Art

J-GLOBAL ID：200902269795524046   Reference number：04A0685535

c-kit gene mutations in intracranial germinomas

頭蓋内はい芽腫におけるc-kit遺伝子の突然変異

Author (6)： SAKUMA Y (Jichi Medical School, Tochigi) ,  SAKURAI S (Jichi Medical School, Tochigi) ,  OGUNI S (Jichi Medical School, Tochigi) ,  SATOH M (Sapporo Medical Univ. Hospital, Sapporo) ,  HIRONAKA M (Jichi Medical School, Tochigi) ,  SAITO K (Jichi Medical School, Tochigi)
Material： Cancer Science  (Cancer Sci)
Volume： 95  Issue： 9  Page： 716-720  Publication year： Sep. 10, 2004 
JST Material Number： F0633A  ISSN： 1347-9032  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *Mutation ,...
Semi thesaurus term： 頭蓋内はい芽腫

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JST classification (2)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N) ,  Molecular genetics in general  (EC02010J)

Reference (33)：

• KITAMURA, Y. A loss-of-function mutation of c-kit results in depletion of mast cells and interstitial cells of Cajal, while its gain-of-function mutation results in their oncogenesis. Mutat Res. 2001, 477, 165-171
• ASHMAN, LK. The biology of stem cell factor and its receptor C-kit. Int J Biochem Cell Biol. 1999, 31, 1037-1051
• ROSSI, P. Role of c-kit in mammalian spermatogenesis. J Endocrinol Invest. 2000, 23, 609-615
• FURITSU, T. Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product. J Clin Invest. 1993, 92, 1736-1744
• LONGLEY, BJ Jr. Activating and dominant inactivating c-KIT catalytic domain mutations in distinct clinical forms of human mastocytosis. Proc Natl Acad Sci USA. 1999, 96, 1609-1614

Terms in the title (4)： 頭蓋 ,  はい芽腫 ,  c-kit遺伝子 ,  突然変異