Art

J-GLOBAL ID：200902269845798614   Reference number：08A0415973

Oxidative stress as a biomarker of respiratory disturbance in patients with severe motor and intellectual disabilities

重症心身障害の患者での呼吸障害のバイオマーカーとしての酸化ストレス

Author (5)： TANUMA Naoyuki (Dep. of Pediatrics, Tokyo Metropolitan Fuchu Medical Center for the Disabled, 2-9-2, Musashidai, Fuchu, Tokyo ...) ,  MIYATA Rie (Dep. of Pediatrics, Tokyo Kita Shakai Hoken Hospital, 4-17-56, Akabanedai, Kita-ku, Tokyo 115-0053, JPN) ,  HAYASHI Masaharu (Dep. of Clinical Neuropathology, Tokyo Metropolitan Inst. for Neuroscience, 2-6, Musashidai, Fuchu, Tokyo 183-8526, JPN) ,  UCHIYAMA Akira (Dep. of Pediatrics, Tokyo Metropolitan Fuchu Medical Center for the Disabled, 2-9-2, Musashidai, Fuchu, Tokyo ...) ,  KURATA Kiyoko (Dep. of Pediatrics, Tokyo Metropolitan Fuchu Medical Center for the Disabled, 2-9-2, Musashidai, Fuchu, Tokyo ...)
Material： Brain & Development  (Brain & Dev)
Volume： 30  Issue： 6  Page： 402-409  Publication year： Jun. 2008 
JST Material Number： W0814A  ISSN： 0387-7604  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *psychosomatic handicapped person ,...
Semi thesaurus term： severe psychosomatic handicapped person

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JST classification (2)： Nervous system diseases  (GN03000O) ,  Respiratory system diseases  (GI03000Z)

Substance index (1)： 8-Hydroxy-2'-deoxyguanosine

Reference (26)：

• Kurihara M, Kumagai K, Noda Y, Watanabe M, Imai M. Prognosis in severe motor and intellectual disabilities syndrome complicated by epilepsy. Brain Dev 1998;20:519-23.
• Hamano K, Kumada S, Hayashi M, Naito R, Hayashida T, Uchiyama A, et al. Laryngeal dystonia in a case of severe motor and intellectual disabilities due to Japanese encephalitis sequelae. Brain Dev 2004;26:335-8.
• Seddon PC, Khan Y. Respiratory problems in children with neurological impairment. Arch Dis Child 2003;88:75-8.
• Simpson EP, Henry YK, Henkel JS, Smith RG, Appel SH. Increased lipid peroxidation in sera of ALS patients: a potential biomarker of disease burden. Neurology 2004;62:1758-65.
• Bogdanov M, Brown RH, Matson W, Smart R, Hayden D, O'Donnell H, et al. Increased oxidative damage to DNA in ALS patients. Free Radical Bio Med 2000;29:652-8.

Terms in the title (5)： 重症心身障害 ,  患者 ,  呼吸障害 ,  バイオマーカー ,  酸化ストレス