Explanation for the failure of neoadjuvant chemotherapy to improve outcomes after radiotherapy for locally advanced uterine cervical cancer from the standpoint of the tumor regression rate

OHARA Kiyoshi; TSUNODA Hajime; OISHI TANAKA Yumiko; OHNISHI Kayoko; NEMOTO Keiko; HASHIMOTO Takayuki; FUKUMITSU Nobuyoshi; HATA Masaharu; SUGAHARA Shinji; TOKUUYE Koichi; YOSHIKAWA Hiroyuki; AKINE Yasuyuki

Art

J-GLOBAL ID：200902271375071393 Reference number：07A0217802

Explanation for the failure of neoadjuvant chemotherapy to improve outcomes after radiotherapy for locally advanced uterine cervical cancer from the standpoint of the tumor regression rate

腫瘍退縮率の視点からの局所進行子宮頚癌の放射線療法後の転帰を改善するためのネオアジュバント化学療法の失敗の説明

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Material：
Volume： 25 Issue： 2 Page： 53-59 Publication year： Feb. 25, 2007
JST Material Number： L3853A ISSN： 0288-2043 CODEN： RAMEER Document type： Article
Article type：原著論文 Country of issue： Japan (JPN) Language： ENGLISH (EN)

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Drug therapy(=pharmacotherapy)for tumors , Radiotherapy for tumors

Reference (16)：

National Cancer Institute. Cervical Cancer (PDQ). Treatment. Available at http://www.cancer.gov/cancertopics/pdq/treatment/cervical/healthprofessional/. Accessed February 28, 2006.
Green JA, Kirwan JM, Tierney JF, Symonds P, Fresco L, Collingwood M, et al. Survival and recurrence after concomitant chemotherapy and radiotherapy for cancer of the uterine cervix: a systematic review and meta-analysis. Lancet 2001; 358: 781-6.
Shueng PW, Hsu WL, Jen YM, Wu CJ, Liu HS. Neoadjuvant chemotherapy followed by radiotherapy should not be a standard approach for locally advanced cervical cancer. Int J Radiat Oncol Biol Phys 1998; 40: 889-96.
Neoadjuvant Chemotherapy for Locally Advanced Cervical Cancer Meta-analysis Collaboration. Neoadjuvant chemotherapy for locally advanced cervical cancer: a systematic review and meta-analysis of individual patient data from 21 randomised trials. Eur J Cancer 2003; 39: 2470-86.
Stehman FB, Bundy BN, DiSaia PJ, Keys HM, Larson JE, Fowler WC. Carcinoma of the cervix treated with radiation therapy. I. A multivariate analysis of prognostic variables in the Gynecologic Oncology Group. Cancer 1991; 67: 2776-85.

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