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J-GLOBAL ID:200902271994900337   Reference number:04A0003993

GLYCOCHENODEOXYCHOLIC ACID INDUCED APOPTOSIS IN RLN-8 HEPATOCYTES

ラット肝細胞(RLN-8)におけるglycochenodeoxycholic acidのアポトーシス誘発作用
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Volume: 63  Issue:Page: 405-414  Publication year: Aug. 28, 2003 
JST Material Number: Z0096B  ISSN: 0037-4342  CODEN: SIGZAL  Document type: Article
Article type: 原著論文  Country of issue: Japan (JPN)  Language: JAPANESE (JA)
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Basic medicine on digestive system 
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Reference (22):
  • 1) Spivey JR, Bronk SG and Gores GJ: Glycochenodeoxycholate-induced lethal cell injury in rat hepatocytes. J Clin Invest 92: 17-24: 1993.
  • 2) Galle PR, Theilmann L, Raedsch R, et al: Ursodeoxycholate reduces hepatotoxicity of bile salts in primary human hepatocytes. Hepatology 12: 486-491, 1990.
  • 3) Faubion WA, Guicciardi ME, Miyoshi H, et al: Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas. J Clin Invest 103: 137-145, 1999.
  • 4) Rodrigues CM, Fan G, Ma X, et al: A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane perturbation. J Clin Invest 101: 2790-2799, 1998.
  • 5) Tsuji M, Kodama K, Okazaki M, et al: Hepatotoxicity of monoamine oxidase in-hibitors in isolated and primary cultured hepatocytes of rat, In monoamine oxidase: basic and clinical aspects. (Ed by Yasuhara H, Parvez SH, Oguchi K, et al) pp. 89-106, VSP, Utrecht, 1993.
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