Nuclear Swelling Occurs during Premature Senescence Mediated by MAP Kinases in Normal Human Fibroblasts

KOBAYASHI Yusuke; SAKEMURA Risa; KUMAGAI Atsuko; SUMIKAWA Emi; FUJII Michihiko; AYUSAWA Dai

Art

J-GLOBAL ID：200902273531947515 Reference number：08A0466237

Nuclear Swelling Occurs during Premature Senescence Mediated by MAP Kinases in Normal Human Fibroblasts

正常ヒト線維芽細胞中のMAPキナーゼが仲介する成熟前老化の間に発生する細胞核の膨張

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Material：
Volume： 72 Issue： 4 Page： 1122-1125 (J-STAGE) Publication year： 2008
JST Material Number： G0021A ISSN： 0916-8451 CODEN： BBBIEJ Document type： Article
Article type：短報 Country of issue： Japan (JPN) Language： ENGLISH (EN)

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Cell physiology in general

Reference (21)：

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SERRANO, M. Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell. 1997, 88, 593-602
SUMIKAWA, E. Prolonged unbalanced growth induces cellular senescence markers linked with mechano transduction in normal and tumor cells. Biochem. Biophys. Res. Commun. 2005, 335, 558-565

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