Art

J-GLOBAL ID：200902275670354530   Reference number：08A0394272

Direct Reprogramming of Terminally Differentiated Mature B Lymphocytes to Pluripotency

最終分化成熟Bリンパ球の多能性への直接再プログラミング

Author (17)： HANNA Jacob (The Whitehead Inst. for Biomedical Res., Cambridge, MA 02142, USA) ,  MARKOULAKI Styliani (The Whitehead Inst. for Biomedical Res., Cambridge, MA 02142, USA) ,  SCHORDERET Patrick (The Whitehead Inst. for Biomedical Res., Cambridge, MA 02142, USA) ,  CAREY Bryce W. (The Whitehead Inst. for Biomedical Res., Cambridge, MA 02142, USA) ,  CAREY Bryce W. (Dep. of Biology, Massachusetts Inst. of Technol., Cambridge, MA 02142, USA) ,  BEARD Caroline (The Whitehead Inst. for Biomedical Res., Cambridge, MA 02142, USA) ,  WERNIG Marius (The Whitehead Inst. for Biomedical Res., Cambridge, MA 02142, USA) ,  CREYGHTON Menno P. (The Whitehead Inst. for Biomedical Res., Cambridge, MA 02142, USA) ,  STEINE Eveline J. (The Whitehead Inst. for Biomedical Res., Cambridge, MA 02142, USA) ,  CASSADY John P. (The Whitehead Inst. for Biomedical Res., Cambridge, MA 02142, USA) ,  CASSADY John P. (Dep. of Biology, Massachusetts Inst. of Technol., Cambridge, MA 02142, USA) ,  FOREMAN Ruth (The Whitehead Inst. for Biomedical Res., Cambridge, MA 02142, USA) ,  FOREMAN Ruth (Dep. of Biology, Massachusetts Inst. of Technol., Cambridge, MA 02142, USA) ,  LENGNER Christopher J. (The Whitehead Inst. for Biomedical Res., Cambridge, MA 02142, USA) ,  DAUSMAN Jessica A. (The Whitehead Inst. for Biomedical Res., Cambridge, MA 02142, USA) ,  JAENISCH Rudolf (The Whitehead Inst. for Biomedical Res., Cambridge, MA 02142, USA) ,  JAENISCH Rudolf (Dep. of Biology, Massachusetts Inst. of Technol., Cambridge, MA 02142, USA)
Material： Cell (Cambridge, Mass.)  (Cell (Camb. Mass.))
Volume： 133  Issue： 2  Page： 250-264  Publication year： Apr. 18, 2008 
JST Material Number： A0707B  ISSN： 0092-8674  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： ES cell ,  *stem cell ,  *cultured cell ,  transgenic mouse ,  RT-PCR ,  gene introduction ,  gene rearrangement ,  DNA binding protein ,  transcription factor ,  oncoprotein ,  gene expression ,  *induced pluripotent stem cell ,  *B cell ,  Sox2 ,  CCAAT-Enhancer-Binding Protein-alpha ,  Pax5 ,  Oct-4 ,  KLF4 ,  Proto-Oncogene Proteins c-myc ,  molecular genetic phenomenon
Semi thesaurus term： *B lymphocyte ,  再プログラミング【遺伝子】 ,  Oct4蛋白質 ,  Klf4蛋白質 ,  c-myc protein

JST classification (2)： Gene expression  (EC02040Q) ,  Cell physiology in general  (EF02010S)

Terms in the title (5)： 分化 ,  成熟 ,  Bリンパ球 ,  多能性 ,  再プログラミング