Art
J-GLOBAL ID：200902276194176314   Reference number：08A1251373

Bioreductive activation of quinone antitumor drugs by mitochondrial voltage-dependent anion channel 1

ミトコンドリアの電圧依存的アニオンチャンネル1によるキノン抗癌剤の生体内還元性活性化
Author (7)：
SIMAMURA Eriko

About SIMAMURA Eriko

(Kanazawa Medical Univ.)

About Kanazawa Medical Univ.

, 
SHIMADA Hiroki

About SHIMADA Hiroki

(Kanazawa Medical Univ.)

About Kanazawa Medical Univ.

, 
ISHIGAKI Yasuhito

About ISHIGAKI Yasuhito

(Kanazawa Medical Univ.)

About Kanazawa Medical Univ.

, 
ISHIGAKI Yasuhito

About ISHIGAKI Yasuhito

(Kanazawa Medical Univ., Ishikawa, JPN)

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, 
HATTA Toshihisa

About HATTA Toshihisa

(Kanazawa Medical Univ.)

About Kanazawa Medical Univ.

, 
HIGASHI Nobuaki

About HIGASHI Nobuaki

(Kanazawa Medical Univ.)

About Kanazawa Medical Univ.

, 
HIRAI Kei-Ichi

About HIRAI Kei-Ichi

(Kanazawa Medical Univ.)

About Kanazawa Medical Univ.


Material：
Anatomical Science International  (Anat Sci Int)

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Volume： 83  Issue： 4  Page： 261-266  Publication year： Dec. 2008 
JST Material Number： W1346A  ISSN： 1447-6959  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)
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quinone

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,...
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*VDAC1

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JST classification (2)：
JST classification
Category name(code) classified by JST.
Biological function 
(EB03040U)

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,  Transport of cell membrane 
(EF04020R)

About Transport of cell membrane

Reference (36)：
  • BACHUR, NR. NADPH cytochrome P-450 reductase activation of quinone anticancer agents to free radicals. Proc Natl Acad Sci USA. 1979, 76, 954-957
  • BAKER, MA. VDAC1 is a transplasma membrane NADH-ferricyanide reductase. J Biol Chem. 2004, 279, 4811-4819
  • COLOMBINI, M. Structure and mode of action of a voltage dependent anion-selective channel (VDAC) located in the outer mitochondrial membrane. Ann N Y Acad Sci. 1980, 341, 552-563
  • CROMPTON, M. Mitochondrial intermembrane junctional complexes and their involvement in cell death. Biochimie. 2002, 84, 143-152
  • DESMOND, JC. The synthetic furanonaphthoquinone induces growth arrest, apoptosis and differentiation in a variety of leukaemias and multiple myeloma cells. Br J Haematol. 2005, 131, 520-529
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Terms in the title (6)：
Terms in the title
Keywords automatically extracted from the title.
ミトコンドリア

About ミトコンドリア

, 
アニオンチャンネル

About アニオンチャンネル

, 
キノン

About キノン

, 
抗癌剤

About 抗癌剤

, 
生体内還元

About 生体内還元

, 
活性化

About 活性化


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