Non-steroidal anti-inflammatory drugs inhibit cellular proliferation and upregulate cyclooxygenase-2 protein expression in endometrial cancer cells

GAO J; NIWA K; SUN W; TAKEMURA M; LIAN Z; ONOGI K; SEISHIMA M; MORI H; TAMAYA T

Art

J-GLOBAL ID：200902277846552891 Reference number：04A0861532

Non-steroidal anti-inflammatory drugs inhibit cellular proliferation and upregulate cyclooxygenase-2 protein expression in endometrial cancer cells

非ステロイド系消炎薬は細胞増殖を阻害し子宮内膜癌細胞のシクロオキシゲナーゼ-2蛋白発現をアップレギュレートする

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Material：
Volume： 95 Issue： 11 Page： 901-907 Publication year： Nov. 10, 2004
JST Material Number： F0633A ISSN： 1347-9032 Document type： Article
Article type：原著論文 Country of issue： Japan (JPN) Language： ENGLISH (EN)

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Basic research of anti-inflammatory drugs , Experimental treatment for tumors , Tumors(=neoplasms)of female genitalia and fetus

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Reference (40)：

AKHMEDKHANOV, A. Role of exogenous and endogenous hormones in endometrial cancer : review of the evidence and research perspectives. Ann N Y Acad Sci. 2001, 943, 296-315
CREASMAN, WT. Influence of cytoplasmic steroid receptor content on prognosis of early stage endometrial carcinoma. Am J Obstet Gynecol. 1985, 151, 922-932
THUN, MJ. Nonsteroidal anti-inflammatory drugs as anticancer agents : mechanistic, pharmacologic, and clinical issues. J Natl Cancer Inst. 2002, 94, 252-266
HULS, G. Non-steroidal anti-inflammatory drugs and molecular carcinogenesis of colorectal carcinomas. Lancet. 2003, 362, 230-232
LIU, CH. Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice. J Biol Chem. 2001, 276, 18563-18569

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