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J-GLOBAL ID：200902277966840980   Reference number：08A0530052

Src-family protein tyrosine kinase negatively regulates cerebellar long-term depression

Srcファミリー蛋白質チロシンキナーゼは小脳長期抑圧を負に制御する

Author (6)： TSURUNO Shun (Dep. of Biophysics, Graduate School of Sci., Kyoto Univ., Kyoto 606-8502, JPN) ,  TSURUNO Shun (CREST, Japan Sci. and Technol. Corp., Kawaguchi, Saitama 332-0012, JPN) ,  KAWAGUCHI Shin-ya (Dep. of Biophysics, Graduate School of Sci., Kyoto Univ., Kyoto 606-8502, JPN) ,  KAWAGUCHI Shin-ya (CREST, Japan Sci. and Technol. Corp., Kawaguchi, Saitama 332-0012, JPN) ,  HIRANO Tomoo (Dep. of Biophysics, Graduate School of Sci., Kyoto Univ., Kyoto 606-8502, JPN) ,  HIRANO Tomoo (CREST, Japan Sci. and Technol. Corp., Kawaguchi, Saitama 332-0012, JPN)
Material： Neuroscience Research  (神経科学)
Volume： 61  Issue： 3  Page： 329-332  Publication year： Jul. 2008 
JST Material Number： D0210C  ISSN： 0168-0102  Document type： Article
Article type： 短報  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： Purkinje cell ,...
Semi thesaurus term： synapse plasticity ,...

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JST classification (1)： Central nervous system  (EJ12030F)

Substance index (1)： PP2

Reference (25)：

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• Canepari, M., Ogden, D., 2003. Evidence for protein tyrosine phosphatase, tyrosine kinase, and G-protein regulation of the parallel fiber metabotropic slow EPSC of rat cerebellar Purkinje neurons. J. Neurosci. 23, 4066-4071.
• De Zeeuw, C.I., Hansel, C., Bian, F., Koekkoek, S.K., van Alphen, A.M., Linden, D.J., Oberdick, J., 1998. Expression of a protein kinase C inhibitor in Purkinje cells blocks cerebellar LTD and adaptation of the vestibuloocular reflex. Neuron 20, 495-508.
• Fadool, D.A., Holmes, T.C., Berman, K., Dagan, D., Levitan, I.B., 1997. Tyrosine phosphorylation modulates current amplitude and kinetics of a neuronal voltage-gated potassium channel. J. Neurophysiol. 78, 1563-1573.

Terms in the title (5)： SRC ,  ファミリー ,  蛋白質チロシンキナーゼ ,  小脳 ,  長期抑圧