Art

J-GLOBAL ID：200902278102897293   Reference number：07A0395903

The functional alteration of mutant GFAP depends on the location of the domain: morphological and functional studies using astrocytoma-derived cells

変異GFAPの機能的変化はドメインの局在性に依存する:星状細胞腫由来細胞を用いた形態学的および機能的研究

Author (6)： YOSHIDA Tomokatsu (Kyoto Prefectural Univ. Medicine, Kyoto, JPN) ,  TOMOZAWA Yasuko (Kyoto Prefectural Univ. Medicine, Kyoto, JPN) ,  ARISATO Takayo (Kagoshima Univ., Kagoshima, JPN) ,  OKAMOTO Yuji (Kagoshima Univ., Kagoshima, JPN) ,  HIRANO Hirofumi (Kyoto Prefectural Univ. Medicine, Kyoto, JPN) ,  NAKAGAWA Masanori (Kyoto Prefectural Univ. Medicine, Kyoto, JPN)
Material： Journal of Human Genetics  (J Hum Genet)
Volume： 52  Issue： 4  Page： 362-369  Publication year： 2007 
JST Material Number： Z0756A  ISSN： 1434-5161  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *Astrocytoma ,...
Semi thesaurus term： variation(biology) ,...

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JST classification (2)： Basic neurology  (GN01020W) ,  Basic oncology in general  (GE02010R)

Reference (33)：

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• BRENNER, M. Mutations in GFAP, encoding glial fibrillary acidic protein, are associated with Alexander disease. Nat Genet. 2001, 27, 277-286
• CARY, RB. Disruption of intermediate filament organization leads to structural defects at the intersomite junction in Xenopus myotomal muscle. Development. 1995, 121, 1041-1052
• FUCHS, E. The cytoskeleton and disease : genetic disorders of intermediate filaments. Ann Rev Genet. 1996, 30, 197-231

Terms in the title (8)： 変異 ,  GFAP ,  ドメイン ,  局在性 ,  星状細胞腫 ,  細胞 ,  形態学 ,  研究