Art

J-GLOBAL ID：200902279696359063   Reference number：03A0262841

Synthesis of Imidazopyridines and Purines as Potent Inhibitors of Leukotriene A₄ Hydrolase.

ロイコトリエンA₄ヒドラーゼの強力な阻害剤としてのイミダゾピリジン類及びプリン類の合成

Author (9)： PENNING T D (Pharmacia Corp., IL, USA) ,  CHANDRAKUMAR N S (Pharmacia Corp., IL, USA) ,  DESAI B N (Pharmacia Corp., IL, USA) ,  DJURIC S W (Pharmacia Corp., IL, USA) ,  GASIECKI A F (Pharmacia Corp., IL, USA) ,  MALECHA J W (Pharmacia Corp., IL, USA) ,  RUSSELL M A (Pharmacia Corp., IL, USA) ,  ASKONAS L J (Pharmacia Corp., IL, USA) ,  SMITH W G (Pharmacia Corp., IL, USA)
Material： Bioorganic & Medicinal Chemistry Letters  (Bioorg Med Chem Lett)
Volume： 13  Issue： 6  Page： 1137-1139  Publication year： Mar. 24, 2003 
JST Material Number： W0248A  ISSN： 0960-894X  Document type： Article
Article type： 短報  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： chemical synthesis ,...
Semi thesaurus term： ロイコトリエンA4

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JST classification (2)： Imidazoles  (CF07083X) ,  Enzyme in general  (EB09010D)

Substance index (21)： SC-22716 ,  1-[2-(4-Benzylphenoxy)ethyl]pyrrolidine ,  p-Toluenesulfonic acid 2-(4-benzylphenoxy)ethyl ester ,  4-Benzylphenyl 2-chloroethyl ether ,  1-[2-(4-Benzylphenoxy)ethyl]-1H-imidazole ,  1-[2-(4-Benzylphenoxy)ethyl]-1H-benzimidazole ,  3-[2-(4-Benzylphenoxy)ethyl]-3H-imidazo[4,5-b]pyridine ,  1-[2-(4-Benzylphenoxy)ethyl]-1H-imidazo[4,5-b]pyridine ,  4-[2-(4-Benzylphenoxy)ethyl]-4H-imidazo[4,5-b]pyridine ,  3-[2-(4-Benzylphenoxy)ethyl]-3H-imidazo[4,5-c]pyridine ,  1-[2-(4-Benzylphenoxy)ethyl]-1H-imidazo[4,5-c]pyridine ,  5-[2-(4-Benzylphenoxy)ethyl]-5H-imidazo[4,5-c]pyridine ,  9-[2-(4-Benzylphenoxy)ethyl]-9H-purine ,  7-[2-(4-Benzylphenoxy)ethyl]-7H-purine ,  3-[2-(4-Benzylphenoxy)ethyl]-3H-purine ,  1-[2-(4-Benzylphenoxy)ethyl]-1H-purine ,  3-[2-(4-Benzylphenoxy)ethyl]-3H-imidazo[4,5-c]pyridine 5-oxide ,  1-[2-(4-Benzylphenoxy)ethyl]-1H-imidazo[4,5-c]pyridine 5-oxide ,  3-[2-(4-Benzylphenoxy)ethyl]-4,5-dihydro-3H-imidazo[4,5-b]pyridine-5-one ,  1-[2-(4-Benzylphenoxy)ethyl]-1H-imidazo[4,5-c]pyridine-4-carbonitrile ,  1-[2-(4-Benzylphenoxy)ethyl]-1H-imidazo[4,5-b]pyridine-5-carbonitrile

Terms in the title (3)： ロイコトリエンA4 ,  阻害剤 ,  プリン類