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J-GLOBAL ID：200902279825704120   Reference number：06A0607716

Foxp3-dependent and -independent molecules specific for CD25⁺CD4⁺ natural regulatory T cells revealed by DNA microarray analysis

DNAマイクロアレイ分析により明らかにしたFoxp3依存的及び非依存的分子特異的CD25⁺CD4⁺ナチュラル調節性T細胞

Author (8)： SUGIMOTO Naoshi (Kyoto Univ., Kyoto, JPN) ,  OIDA Takatoku (Kyoto Univ., Kyoto, JPN) ,  HIROTA Keiji (Kyoto Univ., Kyoto, JPN) ,  NAKAMURA Kyoko (Kyoto Univ., Kyoto, JPN) ,  NOMURA Takashi (Kyoto Univ., Kyoto, JPN) ,  UCHIYAMA Takashi (Kyoto Univ., Kyoto, JPN) ,  SAKAGUCHI Shimon (Kyoto Univ., Kyoto, JPN) ,  SAKAGUCHI Shimon (Japan Sci. and Technol. Agency, Kawaguchi, JPN)
Material： International Immunology  (Int Immunol)
Volume： 18  Issue： 8  Page： 1197-1209  Publication year： Aug. 2006 
JST Material Number： W0116A  ISSN： 0953-8178  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： immunological tolerance ,...
Semi thesaurus term： *調節性T細胞

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JST classification (1)： Immunological reaction in general  (ED03010T)

Reference (47)：

• Sakaguchi, S.2004. Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses. Annu. Rev Immunol.22: 531.
• Shevach, E. M.2002. CD4+ CD25+ suppressor T cells: more questions than answers. Nat. Rev Immunol.2: 389.
• Sakaguchi, S., Sakaguchi, N., Asano, M., Roll, M. and Toda, M.1995. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J. Immunol.155: 1151.
• Asano, M., Toda, M., Sakaguchi, N. and Sakaguchi, S.1996. Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation. J. Exp. Med.184: 387.
• Powrie, F., Correa-Oliveira, R., Mauze, S. and Coffman, R. L.1994. Regulatory interactions between CD45RBhigh and CD45RBIow CD4+ Tcells are important for the balance between protective and pathogenic cell-mediated immunity. J. Exp. Med.179: 589.

Terms in the title (6)： DNAマイクロアレイ ,  分析 ,  FoxP3 ,  非依存 ,  分子 ,  調節性T細胞