Art

J-GLOBAL ID：200902281400570737   Reference number：09A0383178

Structure Revision of Aspergillides A and B, Cytotoxic 14-Membered Macrolides from Aspergillus ostianus, by X-ray Crystallography

Aspergillus ostianusから得たアスペルギリドA及びB,細胞毒性14環マクロライドのX線結晶学的手法による構造の再検討

Author (5)： OOKURA Ryuhei (Fac. of Pharmaceutical Sciences, The Univ. of Tokushima) ,  KITO Keijiro (Fac. of Pharmaceutical Sciences, The Univ. of Tokushima) ,  SAITO Yota (Fac. of Pharmaceutical Sciences, The Univ. of Tokushima) ,  KUSUMI Takenori (Graduate School of Sci. and Engineering, Tokyo Inst. of Technol.) ,  OOI Takashi (Fac. of Pharmaceutical Sciences, The Univ. of Tokushima)
Material： Chemistry Letters  (Chem Lett)
Volume： 38  Issue： 4  Page： 384-384 (J-STAGE)  Publication year： 2009 
JST Material Number： S0742A  ISSN： 0366-7022  CODEN： CMLTAG  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Aspergillus ,  *cytotoxicity ,  *macrocyclic compound ,  *oxygen heterocyclic compound ,  *carboxylate(salt) ,  *aromatic carboxylic acid ,  *aromatic bromine compound ,  X-ray diffraction ,  crystal structure ,  structure analysis ,  stereochemistry ,  absolute configuration ,  proton magnetic resonance
Semi thesaurus term： Aspergillus ostianus ,  *Benzoic Acids

JST classification (2)： Eight or more-membered heterocyclic compounds  (CF07120T) ,  Aromatic monocyclic carboxylic,peroxycarboxylic,and thiocarboxylic acids  (CF05180T)

Substance index (5)： (1β,9E,11α)-5α-Methyl-14α-(3-bromobenzoyloxy)-4,15-dioxabicyclo[9.3.1]pentadeca-9-ene-3-one ,  (1β,9E,11α)-5β-Methyl-14α-(3-bromobenzoyloxy)-4,15-dioxabicyclo[9.3.1]pentadeca-9-ene-3-one ,  3-Bromobenzoic acid ,  Aspergillide A ,  (-)-Aspergillide B

Reference (5)：

• 1) K. Kito, R. Ookura, S. Yoshida, M. Namikoshi, T. Ooi, T. Kusumi, Org. Lett. 2008, 10, 225.
• 2) S. M. Hande, J. Uenishi, Tetrahedron Lett. 2009, 50, 189.
• 3) I. Ohtani, T. Kusumi, Y. Kashman, H. Kakisawa, J. Am. Chem. Soc. 1991, 113, 4092.
• 4) Note without reference.
• 5) Note without reference.

Terms in the title (7)： Aspergillus ,  アスペルギリドA ,  細胞毒性 ,  環 ,  マクロライド ,  X線結晶学 ,  手法