Art

J-GLOBAL ID：200902282955339220   Reference number：04A0296580

Functional and Structural Effects of Mutagenic Replacement of Asn37 at Subsite F on the Lysozyme-catalyzed Reaction

リゾチーム触媒の反応に及ぼすサブサイトFでのAsn37の突然変異置換の機能的および構造的影響

Author (6)： KAWAMURA S (Kyushu Tokai Univ., Kumamoto, JPN) ,  ETO M (Kyushu Tokai Univ., Kumamoto, JPN) ,  IMOTO T (Kyushu Univ., Fukuoka, JPN) ,  IKEMIZU S (Kumamoto Univ., Kumamoto, JPN) ,  ARAKI T (Kyushu Tokai Univ., Kumamoto, JPN) ,  TORIKATA T (Kyushu Tokai Univ., Kumamoto, JPN)
Material： Bioscience, Biotechnology, and Biochemistry  (Bioscience Biotechnology & Biochemistry)
Volume： 68  Issue： 3  Page： 593-601  Publication year： Mar. 23, 2004 
JST Material Number： G0021A  ISSN： 0916-8451  CODEN： BBBIEJ  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

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JST classification (1)： Enzyme in general  (EB09010D)

Reference (26)：

• 1) Blake, C. C. F., Koenig, D. F., Mair, G. A., North, A. C. T., Phillips, D. C., and Sarma, V. R., Structure of hen egg-white lysozyme. A three-dimensional Fourier synthesis at 2 Angstrom resolution. Nature, 206, 757–761 (1965).
• 2) Blake, C. C. F., Johnson, L. N., Mair, G. A., North, A. C. T., Phillips, D. C., and Sarma, V. R., Crystallographic studies on the activity of hen egg white lysozyme. Proc. Roy. Soc. Ser. B, 167, 378–388 (1967).
• 3) Smith, L. J., Sutcliffe, M. J., Redfield, C., and Dobson, C. M., Structure of hen lysozyme in solution. J. Mol. Biol., 229, 930–944 (1993).
• 4) Kuroki, R., Yamada, H., Moriyama, T., and Imoto, T., Chemical mutations of the catalytic carboxyl groups in lysozyme to the corresponding amides. J. Biol. Chem., 261, 13572–13574 (1986).
• 5) Malcolm, B. A., Rosenberg, S., Corey, M. J., Allen, J. S., Baetselier, A. D., and Kirsch, J. F., Site-directed mutagenesis of the catalytic residues Asp-52 and Glu-35 of chicken egg white lysozyme. Proc. Natl. Acad. Sci. USA, 86, 133–137 (1989).

Terms in the title (5)： リゾチーム ,  触媒 ,  サブ ,  突然変異 ,  置換