Art

J-GLOBAL ID：200902285554763622   Reference number：03A0875181

Triiodothyronine but Not Thyroxine Accelerates Myofibrillar Proteolysis via ATP Production in Cultured Muscle Cells

チロキシンは促進しないが,トリヨードチロニンは培養筋肉細胞においてATP生産経由で筋原線維蛋白質分解を促進する

Author (4)： DOI J (Kagoshima Univ., Kagoshima, JPN) ,  OHTSUBO A (Kagoshima Univ., Kagoshima, JPN) ,  OHTSUKA A (Kagoshima Univ., Kagoshima, JPN) ,  HAYASHI K (Kagoshima Univ., Kagoshima, JPN)
Material： Bioscience, Biotechnology, and Biochemistry  (Bioscience Biotechnology & Biochemistry)
Volume： 67  Issue： 11  Page： 2451-2454  Publication year： Nov. 23, 2003 
JST Material Number： G0021A  ISSN： 0916-8451  CODEN： BBBIEJ  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *thyroid hormone ,...

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JST classification (2)： Muscles  (EJ10020G) ,  Thyroid hormones  (EB08030S)

Substance index (4)： Thyroxin ,  Triiodothyronine ,  adenosine triphosphate ,  Nτ-Methylhistidine

Reference (20)：

• 1) Goldberg, A. L., Tischler, M., Demartino, G., and Griffin, G., Hormonal regulation of protein degradation and synthesis in skeletal muscle. Federation Proceedings, 39, 31-36 (1980).
• 2) Nakashima, K., Ohtsuka, A., and Hayashi, K., Comparison of the effects of thyroxine and triiodothyronine on protein turnover and apoptosis in primary chick muscle cell culture. Biochem. Biophys. Res. Commun., 251, 442-448 (1998).
• 3) Brown, J. G., and Millward, D. J., Dose response of protein turnover in rat skeletal muscle to triiodothyronine treatment. Biochim. Biophys. Acta, 757, 182-190 (1983).
• 4) Coux, O., Tanaka, K., and Goldberg, A. L., Structure and functions of 20S and 26S proteasomes. Annu. Rev. Biochem., 65, 801-847 (1996).
• 5) Tawa, N. E., Jr., Odessey, R., and Goldberg, A. L., Inhibitors of the proteasome reduce the accelerated proteolysis in atrophying rat skeletal muscles. J. Clin. Invest., 100, 197-203 (1997).

Terms in the title (8)： チロキシン ,  促進 ,  トリヨードチロニン ,  培養 ,  筋肉細胞 ,  ATP ,  筋原線維蛋白質 ,  分解