Art

J-GLOBAL ID：200902285942168906   Reference number：08A0774198

Increasing the homogeneity, stability and activity of human serum albumin and interferon-α2b fusion protein by linker engineering

リンカー工学によるヒト血清アルブミンとインターフェロンα2bとの融合蛋白質の均一性,安定性及び活性の増加

Author (6)： ZHAO Hong Liang (Dep. of Microorganism Engineering, Beijing Inst. of Biotechnology, 20 Dongdajie Street, Fengtai District, Beijing ...) ,  YAO Xue Qin (Dep. of Microorganism Engineering, Beijing Inst. of Biotechnology, 20 Dongdajie Street, Fengtai District, Beijing ...) ,  XUE Chong (Dep. of Microorganism Engineering, Beijing Inst. of Biotechnology, 20 Dongdajie Street, Fengtai District, Beijing ...) ,  WANG Yang (Dep. of Microorganism Engineering, Beijing Inst. of Biotechnology, 20 Dongdajie Street, Fengtai District, Beijing ...) ,  XIONG Xiang Hua (Dep. of Microorganism Engineering, Beijing Inst. of Biotechnology, 20 Dongdajie Street, Fengtai District, Beijing ...) ,  LIU Zhi Min (Dep. of Microorganism Engineering, Beijing Inst. of Biotechnology, 20 Dongdajie Street, Fengtai District, Beijing ...)
Material： Protein Expression and Purification  (Protein Expression & Purification)
Volume： 61  Issue： 1  Page： 73-77  Publication year： Sep. 2008 
JST Material Number： W0282A  ISSN： 1046-5928  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *Serum Albumin ,  *interferon alpha 2b ,  *fusion protein ,  recombinant protein ,  thermal stability ,  Protein Engineering ,  steric conformation ,  helix structure ,  yield ,  Amino Acid Sequence ,  antiviral action ,  gene introduction ,  storage stability ,  *HSA

JST classification (3)： Cytokines  (EB08090G) ,  Basic research of antiviral drugs  (GW17040O) ,  Gene manipulation  (EC02050B)

Terms in the title (8)： リンカー ,  工学 ,  ヒト血清アルブミン ,  インターフェロンα2b ,  融合蛋白質 ,  均一性 ,  安定性 ,  活性