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J-GLOBAL ID：200902288738328731   Reference number：09A0053684

FIRST SYNTHESIS OF RACEMIC METHYLOPHIOPOGONANONE B AND ITS INHIBITORY ACTIVITY OF HYPOXIA-INDUCIBLE FACTOR-1α

ラセミ体メチルオフィオポゴナノンBの最初の合成及び低酸素誘導因子-1αのその阻害活性

Author (11)： FUJII Mikio (Showa Univ., Tokyo, JPN) ,  FUJII Mikio (Toho Univ., Chiba, JPN) ,  EGAWA Kiyoshi (Showa Univ., Tokyo, JPN) ,  HIRAI Yasuaki (Showa Univ., Tokyo, JPN) ,  KONDO Masato (Showa Univ., Tokyo, JPN) ,  KONDO Masato (Showa Univ., Yokohama, JPN) ,  AKITA Hiroyuki (Toho Univ., Chiba, JPN) ,  NOSE Kiyoshi (Showa Univ., Tokyo, JPN) ,  TORIIZUKA Kazuo (Showa Univ., Tokyo, JPN) ,  IDA Yoshiteru (Showa Univ., Tokyo, JPN) ,  IDA Yoshiteru (Yokohama Coll. Pharmacy, Yokohama, JPN)
Material： Heterocycles  (International Journal for Reviews and Communications in Heterocyclic Chemistry)
Volume： 78  Issue： 1  Page： 207-212  Publication year： Jan. 01, 2009 
JST Material Number： S0966A  ISSN： 0385-5414  CODEN： HTCYAM  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： oxygen heterocyclic compound ,...
Semi thesaurus term： *Chromans ,...

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JST classification (3)： Condensed derivatives of pyrane  (CF07093I) ,  Cyclization reaction,ring-opening reaction  (CF02050I) ,  Synthesis of drugs  (GV01030F)

Substance index (4)： 4-Methoxybenzaldehyde ,  2',4',6'-Trihydroxyacetophenone ,  rac-(3R^*)-3-(4-Methoxybenzyl)-5,7-dihydroxy-6,8-dimethyl-2,3-dihydro-4H-1-benzopyran-4-one ,  rac-(3R^*)-3-(4-Methoxybenzyl)-5,7-dimethoxy-6,8-dimethyl-2,3-dihydro-4H-1-benzopyran-4-one

Reference (13)：

• A. Tada, R. Kasai, T. Saitoh, and J. Shoji, Chem. Pharm. Bull., 1980, 28, 1477.
• A. Tada, R. Kasai, T. Saitoh, and J. Shoji, Chem. Pharm. Bull., 1980, 28, 2039.
• A. Tada, T. Saitoh, and J. Shoji, Chem. Pharm. Bull., 1980, 28, 2487.
• T. Asano, T. Murayama, Y. Hirai, and J. Shoji, Chem. Pharm. Bull., 1993, 41, 391.
• J. B. Harborone,‘The Flavonoids, Advances in Research since 1980’, Chapman and Hall Ltd., New York, 1988, pp. 389-397.

Terms in the title (4)： ラセミ体 ,  メチルオフィオポゴナノンB ,  低酸素誘導因子 ,  阻害活性