Art

J-GLOBAL ID：200902289545902143   Reference number：05A1038307

Biologically Active Glycosides from Asteroidea, 43. Isolation and Structure of a New Neuritogenic-Active Ganglioside Molecular Species from the Starfish Linckia laevigata

Asteroideaからの生物学的に活性なグリコシド 43 ヒトデ,Linckia laevigataからの1種の新しい軸索新生活性ガングリオシド分子種の単離及び構造

Author (4)： INAGAKI Masanori (Graduate School of Pharmaceutical Sciences, Kyushu Univ.) ,  MIYAMOTO Tomofumi (Graduate School of Pharmaceutical Sciences, Kyushu Univ.) ,  ISOBE Ryuichi (Dep. of Medical Electronics Engineering, Fac. of Engineering, Towa Univ.) ,  HIGUCHI Ryuichi (Graduate School of Pharmaceutical Sciences, Kyushu Univ.)
Material： Chemical and Pharmaceutical Bulletin  (Chemical & Pharmaceutical Bulletin)
Volume： 53  Issue： 12  Page： 1551-1554 (J-STAGE)  Publication year： 2005 
JST Material Number： G0504A  ISSN： 0009-2363  CODEN： CPBTAL  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *ganglioside ,...
Semi thesaurus term： Linckia laevigata

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JST classification (2)： Glycosides  (CF10057O) ,  Animal biochemistry  (EJ01050P)

Substance index (15)： (4R)-1-O-[4-O-[3-O-[N-[[N-[(N-Glycoloyl-8-O-methyl-α-neuraminosyloxy)acetyl]-α-neuraminosyloxy]acetyl]-α-neuraminosyl]-β-D-galactopyranosyl]-β-D-glucopyranosyl]-N-[(R)-2-hydroxybehenoyl]-4-hydroxyheptadecasphinganine ,  (4R)-1-O-[4-O-[3-O-[N-[[N-[(N-Glycoloyl-8-O-methyl-α-neuraminosyloxy)acetyl]-α-neuraminosyloxy]acetyl]-α-neuraminosyl]-β-D-galactopyranosyl]-β-D-glucopyranosyl]-N-[(R)-2-hydroxytricosanoyl]-4-hydroxyheptadecasphinganine ,  (4R)-1-O-[4-O-[3-O-[N-[[N-[(N-Glycoloyl-8-O-methyl-α-neuraminosyloxy)acetyl]-α-neuraminosyloxy]acetyl]-α-neuraminosyl]-β-D-galactopyranosyl]-β-D-glucopyranosyl]-N-[(R)-2-hydroxytetracosanoyl]-4-hydroxyheptadecasphinganine ,  1-O-[4-O-[3-O-[N-[[N-[(N-Glycoloyl-8-O-methyl-α-neuraminosyloxy)acetyl]-α-neuraminosyloxy]acetyl]-α-neuraminosyl]-β-D-galactopyranosyl]-β-D-glucopyranosyl]-N-[(R)-2-hydroxybehenoyl]phytosphingosine ,  1-O-[4-O-[3-O-[N-[[N-[(N-Glycoloyl-8-O-methyl-α-neuraminosyloxy)acetyl]-α-neuraminosyloxy]acetyl]-α-neuraminosyl]-β-D-galactopyranosyl]-β-D-glucopyranosyl]-N-[(R)-2-hydroxytricosanoyl]phytosphingosine ,  1-O-[4-O-[3-O-[N-[[N-[(N-Glycoloyl-8-O-methyl-α-neuraminosyloxy)acetyl]-α-neuraminosyloxy]acetyl]-α-neuraminosyl]-β-D-galactopyranosyl]-β-D-glucopyranosyl]-N-[(R)-2-hydroxytetracosanoyl]phytosphingosine ,  (2R)-2-Hydroxybehenic acid ,  Phytosphingosine ,  (4R)-1-O-(4-O-β-D-Galactopyranosyl-β-D-glucopyranosyl)-N-[(R)-2-hydroxybehenoyl]-4-hydroxyheptadecasphinganine ,  (4R)-1-O-(4-O-β-D-Galactopyranosyl-β-D-glucopyranosyl)-N-[(R)-2-hydroxytricosanoyl]-4-hydroxyheptadecasphinganine ,  (4R)-1-O-(4-O-β-D-Galactopyranosyl-β-D-glucopyranosyl)-N-[(R)-2-hydroxytetracosanoyl]-4-hydroxyheptadecasphinganine ,  1-O-(4-O-β-D-Galactopyranosyl-β-D-glucopyranosyl)-N-[(R)-2-hydroxybehenoyl]phytosphingosine ,  1-O-(4-O-β-D-Galactopyranosyl-β-D-glucopyranosyl)-N-[(R)-2-hydroxytricosanoyl]phytosphingosine ,  1-O-(4-O-β-D-Galactopyranosyl-β-D-glucopyranosyl)-N-[(R)-2-hydroxytetracosanoyl]phytosphingosine ,  (4R)-1-O-(4-O-β-D-Galactopyranosyl-β-D-glucopyranosyl)-N-[(R)-2-hydroxytetracosanoyl]-4-hydroxyhexadecasphinganine

Reference (10)：

• 1) Part 42: Higuchi R., Inoue S., Inagaki K., Sakai M., Miyamoto T., Komori T., Inagaki M., Isobe R., Chem. Pharm. Bull., submitted.
• 2) Higuchi R., Inagaki K., Natori T., Komori T., Kawajiri S., Liebigs Ann., 1991, 1—10 (1991).
• 3) Higuchi R., Inukai K., Zhou J. X., Honda M., Komori T., Tsuji S., Nagai Y., Liebigs Ann., 1993, 359—366 (1993).
• 4) Inagaki M., Isobe R., Higuchi R., Eur. J. Org. Chem., 1999, 771—774 (1999).
• 5) Sugiyama S., Honda M., Higuchi R., Komori T., Liebigs Ann., 1991, 349—356 (1991).

Terms in the title (10)： Asteroidea ,  生物学 ,  活性 ,  グリコシド ,  ヒトデ ,  軸索 ,  生活 ,  ガングリオシド ,  分子種 ,  単離