Art

J-GLOBAL ID：200902289700650610   Reference number：04A0627928

Establishment of an Efficient BAC Transgenesis Protocol and its Application to Functional Characterization of the Mouse Brachyury Locus

BACトランスジェニックマウス作製法の確立とその手法を用いたBrachyury遺伝子座の機能解析

Author (5)： ABE K (RIKEN Tsukuba Inst., Ibaraki, JPN) ,  HAZAMA M (Kyoto Univ. Fac. Medicine, Kyoto, JPN) ,  KATOH H (Hamamatsu Univ. School of Medicine, Shizuoka, JPN) ,  YAMAMURA K (Kumamoto Univ., Kumamoto, JPN) ,  SUZUKI M (Kumamoto Univ., Kumamoto, JPN)
Material： Experimental Animals  (実験動物ニュース)
Volume： 53  Issue： 4  Page： 311-320  Publication year： Jul. 2004 
JST Material Number： Z0755A  ISSN： 1341-1357  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *transgenic mouse ,...
Semi thesaurus term： BAC ,...

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JST classification (2)： Laboratry organisms  (EA03070Y) ,  Structure and chemistry of genes  (EC02020U)

Reference (24)：

• 1. Abe, K., Yamamura, K., and Suzuki, M. 2000. Molecular and embryological characterization of a new transgene-induced null allele of mouse Brachyury locus. Mamm. Genome 11: 238-240.
• 2. Antoch, M.P., Song, E.-J., Chang, A.-M., Vitaterna, M.H., Zhao, Y., Wilsbacher, L.D., Sangoram, A.M., King, D.P., Pinto, L.H., and Takahashi, J.S. 1997. Functional identification of the mouse circadian Clock gene by transgenic BAC rescue. Cell 89: 655-667.
• 3. Bennett, D. 1975. The T-locus of the mouse: a review. Cell 28: 463-470.
• 4. Bennett, D. and Dunn, L.C. 1958. Effects on embryonic development of a group of genetically similar lethal alleles derived from different populations of wild house mice. J. Morph. 103: 135-158.
• 5. Chrast, R., Scott, H.S., and Antonarakis, S.E. 1999. Linearization and purification of BAC DNA for the development of transgenic mice. Transgenic Res. 8: 147-150.

Terms in the title (6)： BAC ,  トランスジェニックマウス ,  作製法 ,  手法 ,  Brachyury遺伝子 ,  機能解析