Art
J-GLOBAL ID：200902290741367777   Reference number：08A0746719

Establishment of a luciferase assay-based screening system: Fumitremorgin C selectively inhibits cellular proliferation of immortalized astrocytes expressing an active form of AKT

ルシフェラーゼアッセイに基づくスクリーニング系の確立:フミトレモルギンCは活性型AKT発現不死化星状細胞の細胞増殖を選択的に阻害する
Author (4)：
WANG Lei

About WANG Lei

(Lab. of Molecular and Cellular Pathology, Hokkaido Univ. Graduate School of Medicine, N15 W7, Kita-ku, Sapporo ...)

About Lab. of Molecular and Cellular Pathology, Hokkaido Univ. Graduate School of Medicine, N15 W7, Kita-ku, Sapporo ...

, 
SASAI Ken

About SASAI Ken

(Lab. of Molecular and Cellular Pathology, Hokkaido Univ. Graduate School of Medicine, N15 W7, Kita-ku, Sapporo ...)

About Lab. of Molecular and Cellular Pathology, Hokkaido Univ. Graduate School of Medicine, N15 W7, Kita-ku, Sapporo ...

, 
AKAGI Tsuyoshi

About AKAGI Tsuyoshi

(KAN Res. Inst. Inc., Chuo-ku, Kobe 650-0047, JPN)

About KAN Res. Inst. Inc., Chuo-ku, Kobe 650-0047, JPN

, 
TANAKA Shinya

About TANAKA Shinya

(Lab. of Molecular and Cellular Pathology, Hokkaido Univ. Graduate School of Medicine, N15 W7, Kita-ku, Sapporo ...)

About Lab. of Molecular and Cellular Pathology, Hokkaido Univ. Graduate School of Medicine, N15 W7, Kita-ku, Sapporo ...


Material：
Biochemical and Biophysical Research Communications  (BBRC)

About Biochemical and Biophysical Research Communications


Volume： 373  Issue： 3  Page： 392-396  Publication year： Aug. 29, 2008 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)
Thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
*luciferase

About luciferase

, 
screening (inspection)

About screening (inspection)

, 
astrocyte

About astrocyte

, 
inhibition of multiplication

About inhibition of multiplication

, 
cell immortalization

About cell immortalization

, 
serine-threonine kinase

About serine-threonine kinase

, 
*antitumor drug

About antitumor drug

, 
enzyme inhibitor

About enzyme inhibitor

, 
coculture

About coculture

, 
differentiation (biology)

About differentiation (biology)

, 
developmental physiology

About developmental physiology


Semi thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
Akt

About Akt


JST classification (1)：
JST classification
Category name(code) classified by JST.
Basic research of antitumor(=antineoplastic)drugs 
(GW16010A)

About Basic research of antitumor(=antineoplastic)drugs

Substance index (1)：
Substance index
Chemical Substance indexed to the Article.
Fumitremorgin C

About Fumitremorgin C

Terms in the title (10)：
Terms in the title
Keywords automatically extracted from the title.
ルシフェラーゼアッセイ

About ルシフェラーゼアッセイ

, 
スクリーニング

About スクリーニング

, 
フミトレモルギンC

About フミトレモルギンC

, 
活性

About 活性

, 
AKT

About AKT

, 
発現

About 発現

, 
不死化

About 不死化

, 
星状細胞

About 星状細胞

, 
細胞増殖

About 細胞増殖

, 
阻害

About 阻害


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