Art

J-GLOBAL ID：200902290890555179   Reference number：08A0887798

核内受容体LXRによる糖・脂質代謝制御

Author (1)： SAEZ Enrique (Scripps Res. Inst., California, USA)
Material： Therapeutic Research  (セラピューティック・リサーチ)
Volume： 29  Issue： 8  Page： 1318-1332  Publication year： Aug. 20, 2008 
JST Material Number： Y0681A  ISSN： 0289-8020  Document type： Article
Article type： 解説  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *DNA binding protein ,...
Semi thesaurus term： *cytosol receptor ,...

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JST classification (1)： Receptors on cell membrane  (EF04030C)

Substance index (2)： Glucose ,  Cholesterol

Reference (13)：

• Mangelsdorf DJ, Evans RM. The RXR heterodimers and orphan receptors. Cell 1995; 83: 841-50.
• Shulman AI, Mangelsdorf DJ. Retinoid X receptor heterodimers in the metabolic syndrome. N Engl J Med 2005; 353: 604-15.
• Tontonoz P, Mangelsdorf DJ. Liver X receptor signaling pathways in cardiovascular disease. Mol Endocrinol 2003; 17: 985-93.
• Joseph SB, McKilligin E, Pei L, et al. Synthetic LXR ligand inhibits the development of atherosclerosis in mice. Proc Natl Acad Sci USA 2002; 99: 7604-9.
• Levin N, Bischoff ED, Daige CL, et al. Macrophage liver X receptor is required for antiatherogenic activity of LXR agonists. Arterioscler Thromb Vase Biol 2005; 25: 135-42.

Terms in the title (4)： 核内受容体 ,  LXR ,  糖 ,  脂質代謝