Art

J-GLOBAL ID：200902291113700340   Reference number：07A1175621

The aged thymus shows normal recruitment of lymphohematopoietic progenitors but has defects in thymic epithelial cells

加齢胸腺はリンパ造血前駆細胞の正常動員を示すが,胸腺上皮細胞における障害を有する

Author (6)： GUI Jingang (Univ. Texas Health Center at Tyler, TX, USA) ,  ZHU Xike (Univ. Texas Health Center at Tyler, TX, USA) ,  DOHKAN Junichi (Univ. Texas Health Center at Tyler, TX, USA) ,  CHENG Lili (Univ. Texas Health Center at Tyler, TX, USA) ,  BARNES Peter F. (Univ. Texas Health Center at Tyler, TX, USA) ,  SU Dong-Ming (Univ. Texas Health Center at Tyler, TX, USA)
Material： International Immunology  (Int Immunol)
Volume： 19  Issue： 10  Page： 1201-1211  Publication year： Oct. 2007 
JST Material Number： W0116A  ISSN： 0953-8178  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *thymus gland ,...
Semi thesaurus term： CCL25 ,...

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JST classification (1)： Immunological reaction in general  (ED03010T)

Reference (37)：

• van Ewijk, W., Hollander, G., Terhorst, C. and Wang, B. 2000. Stepwise development of thymic microenvironments in vivo is regulated by thymocyte subsets. Development 127:1583.
• Klug, D. B., Carter, C., Crouch, E., Roop, D., Conti, C. J. and Richie, E. R. 1998. Interdependence of cortical thymic epithelial cell differentiation and T-lineage commitment. Proc. Natl Acad. Sci. USA 95:11822.
• van Ewijk, W., Wang, B., Hollander, G. et al. 1999. Thymic microenvironments, 3-D versus 2-D? Semin. Immunol. 11:57.
• Blackburn, C. C. and Manley, N. R. 2004. Developing a new paradigm for thymus organogenesis. Nat. Rev. Immunol. 4:278.
• Anderson, G., Harman, B. C., Hare, K. J. and Jenkinson, E. J. 2000. Microenvironmental regulation of T cell development in the thymus. Semin. Immunol. 12:457.

Terms in the title (6)： 加齢 ,  胸腺 ,  リンパ ,  造血前駆細胞 ,  胸腺上皮細胞 ,  障害