Art

J-GLOBAL ID：200902291433745627   Reference number：08A0005058

First Stereoselective Synthesis of meso-Secoisolariciresinol and Comparison of Its Biological Activity with (+) and (-)-Secoisolariciresinol

初めてのメソ-セコイソラリシレシノールの立体選択的合成ならびに(+)-および(-)-セコイソラリシレシノールの生物活性の比較

Author (9)： SUGAHARA Takuya (Fac. of Agriculture, Ehime Univ.) ,  YAMAUCHI Satoshi (Fac. of Agriculture, Ehime Univ.) ,  KONDO Ai (Fac. of Agriculture, Ehime Univ.) ,  OHNO Fumi (Fac. of Agriculture, Ehime Univ.) ,  TOMINAGA Siori (Fac. of Agriculture, Ehime Univ.) ,  NAKASHIMA Yuki (Fac. of Agriculture, Ehime Univ.) ,  KISHIDA Taro (Fac. of Agriculture, Ehime Univ.) ,  AKIYAMA Koichi (Integrated Center for Sciences, Ehime Univ.) ,  MARUYAMA Masafumi (Fac. of Agriculture, Ehime Univ.)
Material： Bioscience, Biotechnology, and Biochemistry  (Bioscience Biotechnology & Biochemistry)
Volume： 71  Issue： 12  Page： 2962-2968 (J-STAGE)  Publication year： 2007 
JST Material Number： G0021A  ISSN： 0916-8451  CODEN： BBBIEJ  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： stereospecificity ,...

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JST classification (2)： Biological function  (EB02020R) ,  Other natural substances of biological origin  (CF10090R)

Substance index (3)： Secoisolariciresinol ,  meso-Secoisolariciresinol ,  (+)-Secoisolariciresinol

Reference (27)：

• 1) Ayres, D. C., and Loike, J. D., “Lignans,” Cambridge University Press, New York (1990).
• 2) Ward, S., Lignans, neolignans, and related compounds. Nat. Prod. Rep., 16, 75–96 (1999).
• 3) MacRae, W. D., and Towers, G. H. N., Biological activity of lignans. Phytochemistry, 23, 1207–1220 (1984).
• 4) Saleem, M., Kim, H. J., Ali, M. S., and Lee, Y. S., An update on bioactive plant lignans. Nat. Prod. Rep., 22, 696–716 (2005).
• 5) Ralph, J., Peng, J., Lu, F., Hatfield, R. D., and Helm, R. F., Are lignans optically pure? J. Agric. Food Chem., 47, 2991–2996 (1999).

Terms in the title (3)： セコイソラリシレシノール ,  立体選択的合成 ,  生物活性