Art

J-GLOBAL ID：200902291875435139   Reference number：09A0100430

Targeting cancer with small molecule kinase inhibitors

低分子量キナーゼ阻害剤による癌の標的

Author (3)： ZHANG Jianming (Harvard Medical School, Massachusetts, USA) ,  YANG Priscilla L. (Harvard Medical School, Massachusetts, USA) ,  GRAY Nathanael S. (Harvard Medical School, Massachusetts, USA)
Material： Nature Reviews. Cancer  (Nat Rev Cancer)
Volume： 9  Issue： 1  Page： 28-39  Publication year： Jan. 2009 
JST Material Number： W1368A  ISSN： 1474-175X  Document type： Article
Article type： 文献レビュー  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *enzyme inhibitor ,  *protein kinase ,  low molecular weight ,  *antitumor drug ,  binding site ,  *drug design ,  adenine nucleotide ,  ribonucleotide ,  high energy phosphate compound ,  allosteric effect ,  covalent bond ,  classification ,  intermolecular interaction ,  Proteins ,  protein binding ,  Structure-Activity Relationship ,  selectivity ,  resistance (endure) ,  mechanism

JST classification (3)： Structure-activity relationship of drugs  (GV01050B) ,  Basic research of antitumor(=antineoplastic)drugs  (GW16010A) ,  Basic research of enzyme preparations and enzyme inhibitor preparations  (GW21010W)

Terms in the title (4)： 低分子量 ,  キナーゼ阻害剤 ,  癌 ,  標的