Art

J-GLOBAL ID：200902291954019663   Reference number：09A0283108

Identification of a selective thieno[2,3-c]pyridine inhibitor of COT kinase and TNF-α production

COTキナーゼおよびTNF-α産生の選択性チエノ[2,3-c]ピリジン阻害剤の同定

Author (20)： CUSACK Kevin (Abbott Laboratories, Medicinal Chemistry, 100 Res. Drive, Worcester, MA 01605, USA) ,  ALLEN Hamish (Abbott Laboratories, Medicinal Chemistry, 100 Res. Drive, Worcester, MA 01605, USA) ,  BISCHOFF Agnieszka (Abbott Laboratories, Medicinal Chemistry, 100 Res. Drive, Worcester, MA 01605, USA) ,  CLABBERS Anca (Abbott Laboratories, Medicinal Chemistry, 100 Res. Drive, Worcester, MA 01605, USA) ,  DIXON Richard (Abbott Laboratories, Medicinal Chemistry, 100 Res. Drive, Worcester, MA 01605, USA) ,  FIX-STENZEL Shannon (Abbott Laboratories, Medicinal Chemistry, 100 Res. Drive, Worcester, MA 01605, USA) ,  FRIEDMAN Michael (Abbott Laboratories, Medicinal Chemistry, 100 Res. Drive, Worcester, MA 01605, USA) ,  GAUMONT Yvette (Abbott Laboratories, Medicinal Chemistry, 100 Res. Drive, Worcester, MA 01605, USA) ,  GEORGE Dawn (Abbott Laboratories, Medicinal Chemistry, 100 Res. Drive, Worcester, MA 01605, USA) ,  GORDON Thomas (Abbott Laboratories, Medicinal Chemistry, 100 Res. Drive, Worcester, MA 01605, USA) ,  GRONGSAARD Pintipa (Abbott Laboratories, Medicinal Chemistry, 100 Res. Drive, Worcester, MA 01605, USA) ,  JANSSEN Bernd (Abbott Laboratories, Medicinal Chemistry, 100 Res. Drive, Worcester, MA 01605, USA) ,  JIA Yong (Abbott Laboratories, Medicinal Chemistry, 100 Res. Drive, Worcester, MA 01605, USA) ,  MOSKEY Maria (Abbott Laboratories, Medicinal Chemistry, 100 Res. Drive, Worcester, MA 01605, USA) ,  QUINN Christopher (Abbott Laboratories, Medicinal Chemistry, 100 Res. Drive, Worcester, MA 01605, USA) ,  SALMERON Andres (Abbott Laboratories, Medicinal Chemistry, 100 Res. Drive, Worcester, MA 01605, USA) ,  THOMAS Christine (Abbott Laboratories, Medicinal Chemistry, 100 Res. Drive, Worcester, MA 01605, USA) ,  WALLACE Grier (Abbott Laboratories, Medicinal Chemistry, 100 Res. Drive, Worcester, MA 01605, USA) ,  WISHART Neil (Abbott Laboratories, Medicinal Chemistry, 100 Res. Drive, Worcester, MA 01605, USA) ,  YU Zhengtian (Abbott Laboratories, Medicinal Chemistry, 100 Res. Drive, Worcester, MA 01605, USA)
Material： Bioorganic & Medicinal Chemistry Letters  (Bioorg Med Chem Lett)
Volume： 19  Issue： 6  Page： 1722-1725  Publication year： Mar. 15, 2009 
JST Material Number： W0248A  ISSN： 0960-894X  Document type： Article
Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Terms in the title (6)： COT ,  キナーゼ ,  TNF-α ,  ピリジン ,  阻害剤 ,  同定