Art

J-GLOBAL ID：200902292537503966   Reference number：09A1073985

The Efficacy of S-1 Monotherapy as a 2nd/3rd-Line Therapy for Unresectable Recurrent Colon Cancer

切除不能,再発大腸癌に対するSecond/Third-Line治療としてのS-1単剤療法の有用性

Author (7)： YOKOYAMA TAKEYOSHI (伊勢原協同病院 外科) ,  TOKUHARA HIDENORI (神奈川病院 外科) ,  EGAWA TOMOHISA (済生会 横浜市東部病院 外科) ,  HASHIMOTO OSAMU (大和市病院 外科) ,  SEKI HIROAKI (神奈川県警友会 けいゆう病院 外科) ,  KOYANAGI KAZUO (埼玉医大 国際医療セ 消化器外科) ,  BESSHO TAKASHI (伊勢原協同病院 外科)
Material： 癌と化学療法  (Japanese Journal of Cancer and Chemotherapy)
Volume： 36  Issue： 10  Page： 1667-1670  Publication year： Oct. 15, 2009 
JST Material Number： Z0938A  ISSN： 0385-0684  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： recurrence ,...
Semi thesaurus term： Third line chemotherapy ,...

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JST classification (3)： Tumors(=neoplasms)of digestive system  (GH04000D) ,  Drug therapy(=pharmacotherapy)for tumors  (GE03032C) ,  Clinical application of antitumor(=antineoplastic)drugs  (GW16020L)

Substance index (1)： TS-1

Reference (12)：

• Ohtsu A, Baba H, Sakata Y, et al: Phase II study of S-1, a novel oral fluoropyrimidine derivative, in patients with metastatic colorectal carcinoma. S-1 Cooperative Colorectal Carcinoma Study Group. Br J Cancer 83(2): 141-145, 2000.
• Shirao K, Ohtsu A, Takada H, et al: Phase II study of oral S-1 for treatment of metastatic colorectal carcinoma. Cancer 100(11): 2355-2361, 2004.
• Grothey A, Sargent D, Goldberg RM, et al: Survival of patients with advanced colorectal cancer improves with the availability of fluorouracil-leucovorin, irinotecan, and oxaliplatin in the course of treatment. J Clin Oncol 22(7): 1209-1214, 2004.
• Rougier P and Lepere C: Second-line treatment of patients with metastatic colorectal cancer. Semin Oncol 32 (suppl 9): S48-54, 2005.
• Shirasaka T, Shimamoto Y, Ohshimo H, et al: Development of a novel form of an oral 5-fluorouracil derivative (S-1) directed to the potentiation of the tumor selective cytotoxicity of 5-fluorouracil by two biochemical modulators. Anticancer Drugs 7(5): 548-557, 1996.

Terms in the title (8)： 切除不能 ,  再発大腸癌 ,  LINE ,  治療 ,  S-1 ,  単剤 ,  療法 ,  有用性