Art

J-GLOBAL ID：200902292784667572   Reference number：08A0624014

Effects of pressure on enzyme function of Escherichia coli dihydrofolate reductase

大腸菌ジヒドロ葉酸レダクターゼの酵素機能に対する圧力の影響

Author (7)： OHMAE Eiji (Dep. of Mathematical and Life Sciences, Graduate School of Sci., Hiroshima Univ., Higashi-Hiroshima 739-8526, JPN) ,  TATSUTA Mineyuki (Dep. of Mathematical and Life Sciences, Graduate School of Sci., Hiroshima Univ., Higashi-Hiroshima 739-8526, JPN) ,  ABE Fumiyoshi (Extremobiosphere Res. Center, Japan Marine Sci. and Technol. Center (JAMSTEC), Yokosuka 237-0061, JPN) ,  KATO Chiaki (Extremobiosphere Res. Center, Japan Marine Sci. and Technol. Center (JAMSTEC), Yokosuka 237-0061, JPN) ,  TANAKA Naoki (Dep. of Polymer Sci. and Engineering, Kyoto Inst. of Technol., Kyoto 606-8585, JPN) ,  KUNUGI Shigeru (Dep. of Polymer Sci. and Engineering, Kyoto Inst. of Technol., Kyoto 606-8585, JPN) ,  GEKKO Kunihiko (Dep. of Mathematical and Life Sciences, Graduate School of Sci., Hiroshima Univ., Higashi-Hiroshima 739-8526, JPN)
Material： Biochimica et Biophysica Acta  (BBA. Biomembranes)
Volume： 1784  Issue： 7-8  Page： 1115-1121  Publication year： Jul. 2008 
JST Material Number： B0207A  ISSN： 0005-2728  CODEN： BBBMBS  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *dihydrofolate reductase ,  volume of activation ,  steric conformation ,  hydrostatic pressure ,  conformational transition ,  Michaelis constant ,  Gibbs free energy ,  rate-limiting ,  *pressure effect ,  Escherichia coli ,  coenzyme ,  adenine nucleotide ,  nicotinamide mononucleotide ,  amino acid ,  nitrogen heterocyclic compound ,  aromatic amine ,  aromatic carboxylic acid ,  carboxamide ,  hydroxy compound ,  dicarboxylic acid ,  secondary amine
Semi thesaurus term： rate-determining step

JST classification (1)： Enzyme in general  (EB09010D)

Substance index (2)： NADPH ,  Tetrahydrofolic acid

Terms in the title (3)： 大腸菌 ,  ジヒドロ葉酸レダクターゼ ,  酵素