Art

J-GLOBAL ID：200902293287892178   Reference number：09A0112258

Drug Discovery for Overcoming Chronic Kidney Disease (CKD):Development of Drugs on Endothelial Cell Protection for Overcoming CKD

慢性腎疾患(CKD)を克服するための薬剤発見:CKDを克服するための内皮細胞保護に対する薬剤開発

Author (9)： ISHIZAWA Keisuke (Dep. of Pharmacology, The Inst. of Health Bioscience, The Univ. of Tokushima Graduate School, JPN) ,  YAMAGUCHI Kunihisa (Dep. of Pharmacology, The Inst. of Health Bioscience, The Univ. of Tokushima Graduate School, JPN) ,  HORINOUCHI Yuya (Dep. of Pharmacology, The Inst. of Health Bioscience, The Univ. of Tokushima Graduate School, JPN) ,  FUKUHARA Yayoi (Dep. of Pharmacology, The Inst. of Health Bioscience, The Univ. of Tokushima Graduate School, JPN) ,  TAJIMA Soichiro (Dep. of Pharmacology, The Inst. of Health Bioscience, The Univ. of Tokushima Graduate School, JPN) ,  HAMANO Shuichi (Dep. of Pathological Sci. and Technol., The Inst. of Health Bioscience, The Univ. of Tokushima Graduate School, JPN) ,  TOMITA Shuhei (Dep. of Pharmacology, The Inst. of Health Bioscience, The Univ. of Tokushima Graduate School, JPN) ,  TSUCHIYA Koichiro (Dep. of Medical Pharmacology, The Inst. of Health Bioscience, The Univ. of Tokushima Graduate School, JPN) ,  TAMAKI Toshiaki (Dep. of Pharmacology, The Inst. of Health Bioscience, The Univ. of Tokushima Graduate School, JPN)
Material： Journal of Pharmacological Sciences  (J Pharmacol Sci)
Volume： 109  Issue： 1  Page： 14-19 (J-STAGE)  Publication year： 2009 
JST Material Number： G0813A  ISSN： 1347-8613  Document type： Article
Article type： 文献レビュー  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *endothelial cell ,...
Semi thesaurus term： cell adhesion molecule 1 ,...

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JST classification (3)： Basic medicine on urogenital system  (GM01020T) ,  Basic research of vasoactive drugs and hypotensive drugs  (GW07040J) ,  Basic medicine on cardiovascular system  (GJ01020K)

Substance index (5)： L-NAME ,  Acetylcholine ,  Cumene hydroperoxide ,  Creatinine ,  Nifedipine

Reference (43)：

• ZOCCALI, C. The endothelium as a target in renal diseases. J Nephrol. 2007, 20, S39-S44
• YILMAZ, MI. Serum visfatin concentration and endothelial dysfunction in chronic kidney disease. Nephrol Dial Transplant. 2008, 23, 959-965
• POOLE-WILSON, PA. Effect of long-acting nifedipine on mortality and cardiovascular morbidity in patients with stable angina requiring treatment (ACTION trial) : randomised controlled trial. Lancet. 2004, 364, 849-857
• YUI, Y. Nifedipine retard was as effective as angiotensin converting enzyme inhibitors in preventing cardiac events in high-risk hypertensive patients with diabetes and coronary artery disease : the Japan Multicenter Investigation for Cardiovascular Diseases-B (JMIC-B) subgroup analysis. Hypertens Res. 2004, 27, 449-456
• SHINODA, E. Quantitative coronary angiogram analysis : nifedipine retard versus angiotensin-converting enzyme inhibitors (JMIC-B side arm study). Hypertension. 2005, 45, 1153-1158

Terms in the title (6)： 慢性腎疾患 ,  CKD ,  薬剤 ,  発見 ,  内皮細胞 ,  開発