Selective Inhibition of Eukaryotic Translation Initiation Factor 2α Dephosphorylation Potentiates Fatty Acid-induced Endoplasmic Reticulum Stress and Causes Pancreatic β-Cell Dysfunction and Apoptosis

CNOP Miriam; CNOP Miriam; LADRIERE Laurence; HEKERMAN Paul; ORTIS Fernanda; CARDOZO Alessandra K.; DOGUSAN Zeynep; FLAMEZ Daisy; BOYCE Michael; YUAN Junying; EIZIRIK Decio L.

Art

J-GLOBAL ID：200902293394028729 Reference number：07A0170296

Selective Inhibition of Eukaryotic Translation Initiation Factor 2α Dephosphorylation Potentiates Fatty Acid-induced Endoplasmic Reticulum Stress and Causes Pancreatic β-Cell Dysfunction and Apoptosis

真核生物翻訳開始因子2αの脱リン酸化の選択的阻害は脂肪酸誘導性の小胞体ストレスを助長し膵臓β細胞の機能不全とアポトーシスを引き起こす

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Material：
Volume： 282 Issue： 6 Page： 3989-3997 Publication year： Feb. 09, 2007
JST Material Number： E0038A ISSN： 0021-9258 CODEN： JBCHA3 Document type： Article
Article type：原著論文 Country of issue： United States (USA) Language： ENGLISH (EN)

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Cell physiology in general , Metabolic diseases,nutritional diseases in general.

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