Art

J-GLOBAL ID：200902294587044655   Reference number：07A1149831

Beneficial Effects of the Dual L- and T-Type Ca²⁺ Channel Blocker Efonidipine on Cardiomyopathic Hamsters

心筋症ハムスターに対するL型およびT型Ca²⁺チャンネルブロカー,エホニジピンの有効な作用

Author (8)： SUZUKI Shinsuke (Div. of Cardiology, Dep. of Medicine and Clinical Sci., Yamaguchi Univ. Graduate School of Medicine) ,  OHKUSA Tomoko (Div. of Cardiology, Dep. of Medicine and Clinical Sci., Yamaguchi Univ. Graduate School of Medicine) ,  ONO Katsushige (Dep. of Cardiovascular Sci., Oita Univ. School of Medicine) ,  SATO Takashi (Div. of Cardiology, Dep. of Medicine and Clinical Sci., Yamaguchi Univ. Graduate School of Medicine) ,  YOSHIDA Masa-aki (Div. of Cardiology, Dep. of Medicine and Clinical Sci., Yamaguchi Univ. Graduate School of Medicine) ,  YANO Masafumi (Div. of Cardiology, Dep. of Medicine and Clinical Sci., Yamaguchi Univ. Graduate School of Medicine) ,  TAKEBAYASHI Satoshi (Dep. of Cardiovascular Sci., Oita Univ. School of Medicine) ,  MATSUZAKI Masunori (Div. of Cardiology, Dep. of Medicine and Clinical Sci., Yamaguchi Univ. Graduate School of Medicine)
Material： Circulation Journal  (Circ J)
Volume： 71  Issue： 12  Page： 1970-1976 (J-STAGE)  Publication year： 2007 
JST Material Number： F0908A  ISSN： 1346-9843  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Cricetinae ,...
Semi thesaurus term： ejection fraction

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JST classification (2)： Basic research of vasoactive drugs and hypotensive drugs  (GW07040J) ,  Basic medicine on cardiovascular system  (GJ01020K)

Substance index (1)： Efonidipine

Reference (27)：

• NUSS, HB. T-type Ca^<2+> current is expressed in hypertrophied adult feline left ventricular myocytes. Circ Res. 1993, 73, 777-782
• MARTINEZ, ML. Expression of T-type Ca^<2+> channels in ventricular cells from hypertrophied rat hearts. J Mol Cell Cardiol. 1999, 31, 1617-1625
• SEN, L. T-type Ca^<2+> channels are abnormal in genetically determined cardiomyopathic hamster hearts. Circ Res. 1994, 75, 149-155
• HUANG, B. Reexpression of T-type Ca^<2+> channel gene and current in post-infarction remodeled rat left ventricle. Cardiovasc Res. 2000, 46, 442-449
• IZUMI, T. Reinduction of T-type calcium channels by endothelin-1 in failing hearts in vivo and in adult rat ventricular myocytes in vitro. Circulation. 2003, 108, 2530-2535

Terms in the title (5)： 心筋症 ,  ハムスター ,  L型 ,  T型Ca2+チャンネル ,  エホニジピン