Art

J-GLOBAL ID：200902295683895280   Reference number：08A0016886

Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling

ハイスループット腫よう細胞系概観法を用いた選択キナーゼ阻害剤に対する遺伝子型関連感受性の同定

Author (25)： MCDERMOTT Ultan (Harvard Medical School, MA) ,  SHARMA Sreenath V. (Harvard Medical School, MA) ,  DOWELL Lori (Harvard Medical School, MA) ,  GRENINGER Patricia (Harvard Medical School, MA) ,  MONTAGUT Clara (Harvard Medical School, MA) ,  LAMB Jennifer (Harvard Medical School, MA) ,  ARCHIBALD Heidi (Harvard Medical School, MA) ,  RAUDALES Raul (Harvard Medical School, MA) ,  TAM Angela (Harvard Medical School, MA) ,  LEE Diana (Harvard Medical School, MA) ,  ROTHENBERG S.Michael (Harvard Medical School, MA) ,  SUPKO Jeffrey G. (Harvard Medical School, MA) ,  SORDELLA Raffaella (Harvard Medical School, MA) ,  ULKUS Lindsey E. (Harvard Medical School, MA) ,  IAFRATE A.John (Harvard Medical School, MA) ,  MAHESWARAN Shyamala (Harvard Medical School, MA) ,  NJAUW Ching Ni (Massachusetts General Hospital, MA) ,  TSAO Hensin (Massachusetts General Hospital, MA) ,  DREW Lisa (AstraZeneca R&D Boston, MA) ,  HANKE Jeff H. (AstraZeneca R&D Boston, MA) ,  MA Xiao-Jun (AviaraDx, Inc., CA) ,  ERLANDER Mark G. (AviaraDx, Inc., CA) ,  GRAY Nathanael S. (Harvard Medical School, MA) ,  HABER Daniel A. (Harvard Medical School, MA) ,  SETTLEMAN Jeffrey (Harvard Medical School, MA)
Material： Proceedings of the National Academy of Sciences of the United States of America  (PNAS)
Volume： 104  Issue： 50  Page： 19936-19941  Publication year： Dec. 11, 2007 
JST Material Number： D0387A  ISSN： 0027-8424  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： evaluation ,...
Semi thesaurus term： B-raf Kinases ,...

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JST classification (2)： Basic research of antitumor(=antineoplastic)drugs  (GW16010A) ,  Basic research of enzyme preparations and enzyme inhibitor preparations  (GW21010W)

Substance index (3)： Imatinib ,  Erlotinib ,  AZ-628

Terms in the title (6)： ハイスループット ,  腫よう細胞系 ,  キナーゼ阻害剤 ,  遺伝子型 ,  感受性 ,  同定