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J-GLOBAL ID：200902295804430964   Reference number：07A1078988

Pauferrol A, a novel chalcone trimer with a cyclobutane ring from Caesalpinia ferrea mart exhibiting DNA topoisomerase II inhibition and apoptosis-inducing activity

Caesalpinia ferrea mart由来のDNAトポイソメラーゼII阻害及びアポプトーシス誘発活性を示す新規なシクロブタン環含有カルコン三量体,パウフェロールA

Author (10)： NOZAKI Hiroshi (Dep. of Biochemistry, Fac. of Sci., Okayama Univ. of Sci., 1-1 Ridai-cho, Okayama 700-0005, JPN) ,  HAYASHI Ken-ichiro (Dep. of Biochemistry, Fac. of Sci., Okayama Univ. of Sci., 1-1 Ridai-cho, Okayama 700-0005, JPN) ,  KIDO Masahiro (Integrated Center for Sciences (INCS), Ehime Univ., Bunkyo-cho, Matsuyama 790-8577, JPN) ,  KAKUMOTO Kazuyuki (Dep. of Biochemistry, Fac. of Sci., Okayama Univ. of Sci., 1-1 Ridai-cho, Okayama 700-0005, JPN) ,  IKEDA Shogo (Dep. of Biochemistry, Fac. of Sci., Okayama Univ. of Sci., 1-1 Ridai-cho, Okayama 700-0005, JPN) ,  MATSUURA Nobuyasu (Dep. of Life Sci., Fac. of Sci., Okayama Univ. of Sci., 1-1 Ridai-cho, Okayama 700-0005, JPN) ,  TANI Hiroyuki (Integrated Center for Sciences (INCS), Ehime Univ., Bunkyo-cho, Matsuyama 790-8577, JPN) ,  TAKAOKA Daisuke (Dep. of Chemistry, Fac. of Education, Ehime Univ., Bunkyo-cho, Matsuyama 790-8577, JPN) ,  IINUMA Munekazu (Dep. of Pharmacognosy, Gifu Pharmaceutical Univ., 6-1 Mitahora-higashi 5-choume, Gifu 502-8585, JPN) ,  AKAO Yukihiro (Gifu International Inst. of Biotechnology, 1-1Naka-Fudogaoka, Kakamigahara, Gifu 504-0838, JPN)
Material： Tetrahedron Letters  (Tetrahedron Lett)
Volume： 48  Issue： 47  Page： 8290-8292  Publication year： Nov. 19, 2007 
JST Material Number： E0366A  ISSN： 0040-4039  Document type： Article
Article type： 短報  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *alicyclic compound ,...
Semi thesaurus term： Caesalpinia ferrea

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JST classification (2)： Other natural substances of biological origin  (CF10090R) ,  Plant biochemistry  (EH01050J)

Substance index (1)： Pauferrol A

Terms in the title (9)： Caesalpinia ,  DNAトポイソメラーゼII ,  阻害 ,  アポプトーシス ,  誘発 ,  活性 ,  シクロブタン ,  カルコン ,  三量体