Valproic Acid-induced Hearing Loss and Tinnitus

HORI A; KATAOKA S; SAKAI K; HIROSE G; IWASAKI N; HORIGUCHI A; TAKASHIMA M; TOMODA K

Art

J-GLOBAL ID：200902295924174732 Reference number：03A0873717

Valproic Acid-induced Hearing Loss and Tinnitus

バルプロ酸による難聴と耳鳴

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Author (8)： , , , , , , ,
Material：
Volume： 42 Issue： 11 Page： 1153-1154 Publication year： Nov. 2003
JST Material Number： Z0157B ISSN： 0918-2918 Document type： Article
Article type：短報 Country of issue： Japan (JPN) Language： ENGLISH (EN)

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Diseases of ear,nose,pharynx and larynx , Clinical applications of antiepileptics and anticonvulsants

Reference (3)：

1) Armon C, Brown E, Carwile S, Miller P, Shin C. Sensorineuronal hearing loss: a reversible effect of valproic acid. Neurology 40: 1896-1898, 1990.
2) McLean MJ, Macdonald RL. Sodium valproate, but not ethosuximide, produces use- and voltage-dependent limitation of high frequency repetitive firing of action potentials of mouse central neurons in cell culture. J Pharmacol Exp Ther 237: 1001-1011, 1986.
3) Franceschetti S, Hamon B, Heinemann U. The action of valproate on spontaneous epileptiform activity in the absence of synaptic transmission and on evoked changes in [Ca2+]o and [K+]o in the hippocampal slice. Brain Res 386: 1-11, 1986.

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