Art

J-GLOBAL ID：200902297497751939   Reference number：03A0653382

Hemoglobin Variant HbG-Coushatta (β-22 Glu→Ala) Found by Dissociation of Blood Glucose from Values of HbA_1C Measured by HPLC

HPLCによって測定されたHbA_1Cの値から血中グルコースが解離することから見いだされたヘモグロビンのバリアントHbG-coushatta(β-22Glu→Ala)

Author (6)： OGAWA K (Kitasako Clinic, Tokushima) ,  BANDO T (Kitasako Clinic, Tokushima) ,  OGAWA M (Kitasako Clinic, Tokushima) ,  MIYAZAKI A (Osaka Medical Coll., Osaka) ,  NAKANISHI T (Osaka Medical Coll., Osaka) ,  SHIMIZU A (Osaka Medical Coll., Osaka)
Material： Internal Medicine  (Intern Med)
Volume： 42  Issue： 9  Page： 781-787  Publication year： Sep. 2003 
JST Material Number： Z0157B  ISSN： 0918-2918  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Hemoglobin A ,...
Semi thesaurus term： HbG-Coushatta

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JST classification (1)： Clinical hematology in general  (GK01030Y)

Reference (10)：

• 1) Nakanishi T, Miyazaki A, Kishikawa M, et al. Quantification of glycated hemoglobin by electrospray ionization mass spectrometry. J Mass Spectrom 32: 773-778, 1997.
• 2) Nakanishi T, Miyazaki A, Shimizu A, Yamaguchi A, Nishimura S. Assessment of the effect of hemoglobin variants on routine HbA_1c measurements by electrospray ionization mass spectrometry. Clin Chim Acta 323: 89-101, 2002.
• 3) Bisse E, Wieland H. High-performance liquid chromatographic separation of human haemoglobins. Simultaneous determination of foetal and glycated haemoglobins. J Chromatogr 434: 95-110, 1988.
• 4) Nakanishi T, Miyazaki A, Kishikawa M, et a). A new hemoglobin variant found during HbA_1c measurement: Hb Hokusetsu [β52 (D3) Asp→Gly]. Hemoglobin 22: 355-371, 1998.
• 5) Nakanishi T, Miyazaki A, Kishikawa M, Shimizu A, Aoki Y, Kikuchi M. Hb Peterborough [β111 (G13) Val→Phe] in Japan; Rapid identification by ESI/MS using proteolytic digests of oxidized globin. Hemoglobin 22: 23-35, 1998.

Terms in the title (6)： HPLC ,  HbA1c ,  血中グルコース ,  解離 ,  ヘモグロビン ,  バリアント