High LET radiation enhances apoptosis in mutated p53 cancer cells through Caspase-9 activation

YAMAKAWA Nobuhiro; TAKAHASHI Akihisa; MORI Eiichiro; IMAI Yuichiro; FURUSAWA Yoshiya; OHNISHI Ken; KIRITA Tadaaki; OHNISHI Takeo

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J-GLOBAL ID：200902297552141738 Reference number：08A0630180

High LET radiation enhances apoptosis in mutated p53 cancer cells through Caspase-9 activation

高LET放射はカスパーゼ9活性化を通して変異p53癌細胞におけるアポトーシスを増加させる

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Material：
Volume： 99 Issue： 7 Page： 1455-1460 Publication year： Jul. 2008
JST Material Number： W1423A ISSN： 1347-9032 Document type： Article
Article type：原著論文 Country of issue： Australia (AUS) Language： ENGLISH (EN)

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Experimental treatment for tumors , Tumors(=neoplasms)of tooth and mouth(=oral cavity) , Basic radiology , Biological function

Reference (35)：

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HOLLSTEIN, M. p53 mutations in human cancers. Science. 1991, 253, 49-53
EFEYAN, A. p53 : guardian of the genome and policeman of the oncogenes. Cell Cycle. 2007, 6, 1006-1010
VOUSDEN, KH. Live or let die : the cell's response to p53. Nat Rev Cancer. 2002, 2, 594-604

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