Art

J-GLOBAL ID：200902298865725338   Reference number：09A0189258

Quercetin Glucuronide Inhibits Cell Migration and Proliferation by Platelet-Derived Growth Factor in Vascular Smooth Muscle Cells

ケルセチン・グルクロニドは,血管平滑筋細胞中の血小板由来増殖因子による細胞の遊走と増殖を抑制する

Author (10)： ISHIZAWA Keisuke (Dep. of Pharmacology, The Inst. of Health Bioscience, The Univ. of Tokushima Graduate School, JPN) ,  IZAWA-ISHIZAWA Yuki (Dep. of Pharmacology, The Inst. of Health Bioscience, The Univ. of Tokushima Graduate School, JPN) ,  OHNISHI Sachiyo (Dep. of Clinical Pharmacy, The Inst. of Health Bioscience, The Univ. of Tokushima Graduate School, JPN) ,  MOTOBAYASHI Yuki (Dep. of Pharmacology, The Inst. of Health Bioscience, The Univ. of Tokushima Graduate School, JPN) ,  KAWAZOE Kazuyoshi (Dep. of Clinical Pharmacy, The Inst. of Health Bioscience, The Univ. of Tokushima Graduate School, JPN) ,  HAMANO Shuichi (Dep. of Pathological Sci. and Technol., The Inst. of Health Bioscience, The Univ. of Tokushima Graduate School, JPN) ,  TSUCHIYA Koichiro (Dep. of Medical Pharmacology, The Inst. of Health Bioscience, The Univ. of Tokushima Graduate School, JPN) ,  TOMITA Shuhei (Dep. of Pharmacology, The Inst. of Health Bioscience, The Univ. of Tokushima Graduate School, JPN) ,  MINAKUCHI Kazuo (Dep. of Clinical Pharmacy, The Inst. of Health Bioscience, The Univ. of Tokushima Graduate School, JPN) ,  TAMAKI Toshiaki (Dep. of Pharmacology, The Inst. of Health Bioscience, The Univ. of Tokushima Graduate School, JPN)
Material： Journal of Pharmacological Sciences  (J Pharmacol Sci)
Volume： 109  Issue： 2  Page： 257-264 (J-STAGE)  Publication year： 2009 
JST Material Number： G0813A  ISSN： 1347-8613  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： glycoside ,...
Semi thesaurus term： Akt ,...

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JST classification (1)： Basic medicine on cardiovascular system  (GJ01020K)

Substance index (3)： Quercetin ,  Acetylcysteine ,  Diphenyleneiodonium chloride

Reference (40)：

• FORMICA, JV. Review of the biology of quercetin and related bioflavonoids. Food Chem Toxicol. 1995, 33, 1061-1080
• PEREZ-VIZCAINO, F. The flavonoid quercetin induces apoptosis and inhibits JNK activation in intimal vascular smooth muscle cells. Biochem Biophys Res Commun. 2006, 346, 919-925
• BUCKI, R. Flavonoid inhibition of platelet procoagulant activity and phosphoinositide synthesis. J Thromb Haemost. 2003, 1, 1820-1828
• HANASAKI, Y. The correlation between active oxygens scavenging and antioxidative effects of flavonoids. Free Radic Biol Med. 1994, 16, 845-850
• HAYEK, T. Reduced progression of atherosclerosis in apolipoprotein E-deficient mice following consumption of red wine, or its polyphenols quercetin or catechin, is associated with reduced susceptibility of LDL to oxidation and aggregation. Arterioscler Thromb Vasc Biol. 1997, 17, 2744-2752

Terms in the title (7)： ケルセチン ,  グルクロニド ,  血管平滑筋細胞 ,  血小板由来増殖因子 ,  細胞 ,  遊走 ,  増殖