Art

J-GLOBAL ID：200902299790120687   Reference number：05A0132439

Psoriasis is characterized by altered epidermal expression of caspase 14, a novel regulator of keratinocyte terminal differentiation and barrier formation

乾せんはケラチン細胞終末分化およびバリアー生成の新しいレギュレーター,カスパーゼ14の変化した表皮発現により特徴付けられる

Author (7)： WALSH D S (Dermatology Serv., GA, USA) ,  BORKE J L (Medical Coll. of Georgia, GA, USA) ,  SINGH B B (Medical Coll. of Georgia, GA, USA) ,  DO N-N (Medical Coll. of Georgia, GA, USA) ,  HSU S D (Medical Coll. of Georgia, GA, USA) ,  BALAGON M V (Leonard Wood Memorial Center for Leprosy Res., Cebu City, PHL) ,  ABALOS R M (Leonard Wood Memorial Center for Leprosy Res., Cebu City, PHL)
Material： Journal of Dermatological Science  (J Dermatol Sci)
Volume： 37  Issue： 1  Page： 61-63  Publication year： Jan. 2005 
JST Material Number： W1280A  ISSN： 0923-1811  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *psoriasis ,...

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JST classification (1)： Basic dermatology  (GF01020Y)

Reference (10)：

• CHIEN, AJ. Processing of native caspase-14 occurs at an atypical cleavage site in normal epidermal differentiation. Biochem Biophys Res Commun. 2002, 296, 911-917
• HU, S. Caspase-14 is a novel developmentally regulated protease. J Biol Chem. 1998, 273, 29648-29653
• VAN DE CRAEN, M. Identification of a new caspase homologue : caspase-14. Cell Death Differ. 1998, 5, 838-846
• LIPPENS, S. Caspase-14 is expressed in the epidermis, the choroid plexus, the retinal pigment epithelium and thymic Hassall's bodies. Cell Death Differ. 2003, 10, 257-259
• LIPPENS, S. Epidermal differentiation does not involve the pro-apoptotic executioner caspases, but is associated with caspase-14 induction and processing. Cell Death Differ. 2000, 7, 1218-1224

Terms in the title (8)： 乾せん ,  ケラチン細胞 ,  分化 ,  バリアー ,  レギュレーター ,  カスパーゼ14 ,  表皮 ,  発現