Pat
J-GLOBAL ID:200903077642607730

毒性物質の検出方法

Inventor:
Applicant, Patent owner:
Agent (1): 青山 葆 (外2名)
Gazette classification:公開公報
Application number (International application number):2001255380
Publication number (International publication number):2003061673
Application date: Aug. 24, 2001
Publication date: Mar. 04, 2003
Summary:
【要約】【課題】 毒性物質を生物学的な方法により検出する。【解決手段】 被検物質の存在下に、以下の酵母遺伝子、及び該酵母遺伝子に相同性の他種由来の遺伝子よりなる群から選択される遺伝子を含む細胞から発現される該遺伝子に対応するmRNAを測定して毒性物質を検出する。
Claim (excerpt):
被検物質の存在下に、YBR072W、YCR102C、YCR107W、YDL218W、YDL243C、YDR453C、YDR533C、YFL014W、YFL056C、YFL057C、YGR110W、YJR155W、YKL071W、YKR076W、YLL060C、YLR460C、YMR090W、YNL331C、YNL332W、YNL335W、YOL150C、YOL165C、YPL171C、YPR167C、YBL048W、YBL064C、YBL107C、YBR008C、YBR173C、YBR256C、YBR296C、YDL021W、YFL022C、YFL024C、YFL061W、YGL121C、YGL158W、YGR043C、YHR029C、YHR112C、YHR139C、YHR179W、YHR209W、YIR030C、YJR010W、YJR048W、YKL001C、YKL107W、YKR075C、YKR097W、YLL056C、YLR297W、YLR303W、YML087C、YMR096W、YNL274C、YOL151W、YOR226C、YOR338W、YOR391C、YPL280W、YDR406W、YJL153C、YLR346C、YOR049C、YOR153W、YPL088W、YAL034C、YDL124W、YDL174C、YDR476C、YGL156W、YGR035C、YGR157W、YGR213C、YGR281W、YGR284C、YHL047C、YHR043C、YHR044C、YHR054C、YJR073C、YKL165C、YLR008C、YMR315W、YNL211C、YOL031C、YOL101C、YOR303W、YAL005C、YAR031W、YBL005W-A、YBL022C、YBL041W、YBL049W、YBL075C、YBL078C、YBR062C、YBR169C、YBR294W、YCL020W、YCL035C、YCL043C、YCL050C、YCL057W、YCR012W、YCR013C、YCR060W、YDL007W、YDL027C、YDL097C、YDL110C、YDL126C、YDL169C、YDR070C、YDR155C、YDR158W、YDR204W、YDR210W、YDR214W、YDR258C、YDR313C、YDR368W、YDR435C、YER012W、YER037W、YER091C、YER103W、YFL044C、YFR003C、YFR010W、YFR020W、YFR024C、YFR044C、YFR053C、YGL006W、YGL048C、YGL062W、YGL141W、YGL157W、YGL163C、YGL180W、YGL184C、YGR010W、YGR028W、YGR032W、YGR048W、YGR124W、YGR135W、YGR142W、YGR161C、YGR192C、YGR197C、YGR201C、YGR212W、YGR231C、YGR244C、YGR254W、YGR268C、YHL030W、YHR016C、YHR018C、YHR055C、YHR087W、YHR166C、YIL160C、YIR017C、YJL034W、YJL048C、YJL052W、YJL144W、YJL163C、YJR009C、YJR069C、YJR074W、YJR130C、YJR149W、YKL065C、YKL073W、YKL103C、YKL142W、YKL210W、YKL218C、YKR011C、YKR018C、YKR046C、YKR049C、YLL024C、YLL026W、YLR027C、YLR080W、YLR107W、YLR121C、YLR132C、YLR133W、YLR155C、YLR158C、YLR161W、YLR195C、YLR217W、YLR328W、YLR336C、YLR345W、YLR370C、YLR423C、YML004C、YML092C、YML128C、YML130C、YML131W、YMR040W、YMR118C、YMR214W、YMR251W、YMR297W、YMR322C、YNL036W、YNL055C、YNL071W、YNL094W、YNL134C、YNL155W、YNL160W、YNL239W、YNL241C、YOL005C、YOR020C、YOR027W、YOR037W、YOR059C、YOR120W、YOR134W、YOR152C、YOR173W、YOR289W、YOR362C、YPL240C、YPR030W、YAL008W、YAL023C、YAL060W、YAL062W、YAR009C、YBL101C、YBR006W、YBR046C、YBR052C、YBR053C、YBR056W、YBR099C、YBR137W、YBR139W、YBR149W、YBR170C、YBR177C、YBR203W、YBR207W、YBR212W、YBR239C、YBR284W、YBR293W、YCL018W、YCL033C、YCL040W、YCL049C、YCR062W、YCR067C、YCR082W、YDL010W、YDL020C、YDL024C、YDL054C、YDL095W、YDL100C、YDL115C、YDL144C、YDL198C、YDL223C、YDL245C、YDL246C、YDR001C、YDR032C、YDR058C、YDR072C、YDR127W、YDR168W、YDR169C、YDR188W、YDR231C、YDR261C、YDR264C、YDR272W、YDR293C、YDR304C、YDR330W、YDR403W、YDR411C、YDR427W、YDR436W、YDR497C、YDR511W、YDR516C、YDR519W、YDR545W、YEL012W、YEL030W、YER004W、YER009W、YER021W、YER035W、YER053C、YER079W、YER094C、YER096W、YER125W、YER158C、YER163C、YER175C、YER177W、YER178W、YER185W、YFL006W、YFL010C、YFL016C、YFL029C、YFL030W、YFL031W、YFL032W、YFL038C、YFL041W、YFR004W、YFR047C、YFR050C、YFR052W、YGL011C、YGL013C、YGL037C、YGL047W、YGL053W、YGL091C、YGL094C、YGL127C、YGL150C、YGL199C、YGL207W、YGL248W、YGR008C、YGR037C、YGR055W、YGR101W、YGR130C、YGR154C、YGR194C、YGR221C、YGR232W、YGR248W、YGR253C、YGR256W、YHL008C、YHR027C、YHR053C、YHR057C、YHR111W、YHR138C、YHR161C、YHR164C、YHR169W、YHR174W、YHR176W、YHR199C、YIL010W、YIL034C、YIL041W、YIL045W、YIL087C、YIL107C、YIL142W、YIL155C、YIR034C、YIR036C、YIR037W、YIR038C、YIR039C、YJL001W、YJL031C、YJL035C、YJL053W、YJL057C、YJL066C、YJL068C、YJL082W、YJL099W、YJL102W、YJL151C、YJL152W、YJL161W、YJL164C、YJL171C、YJL172W、YJL210W、YJL219W、YJR008W、YJR045C、YJR046W、YJR106W、YJR117W、YJR137C、YKL007W、YKL026C、YKL035W、YKL091C、YKL104C、YKL117W、YKL145W、YKL146W、YKL151C、YKL152C、YKL153W、YKL193C、YKL195W、YKL213C、YKL215C、YLL028W、YLL039C、YLL058W、YLR054C、YLR103C、YLR120C、YLR136C、YLR149C、YLR152C、YLR178C、YLR259C、YLR299W、YLR324W、YLR327C、YLR348C、YLR350W、YLR356W、YLR362W、YLR387C、YLR429W、YML054C、YML070W、YML100W、YML117W、YML125C、YMR004W、YMR008C、YMR009W、YMR020W、YMR067C、YMR089C、YMR097C、YMR102C、YMR105C、YMR107W、YMR152W、YMR180C、YMR184W、YMR191W、YMR219W、YMR271C、YMR275C、YMR295C、YMR314W、YMR316W、YNL006W、YNL007C、YNL012W、YNL044W、YNL045W、YNL074C、YNL092W、YNL093W、YNL104C、YNL115C、YNL156C、YNL231C、YNL234W、YNL237W、YNL281W、YNL305C、YNL333W、YNR010W、YNR019W、YNR033W、YNR059W、YNR068C、YNR069C、YOL032W、YOL036W、YOL047C、YOL071W、YOL082W、YOL083W、YOL117W、YOL119C、YOL126C、YOL131W、YOL153C、YOL162W、YOL163W、YOL164W、YOR019W、YOR035C、YOR036W、YOR099W、YOR117W、YOR124C、YOR130C、YOR132W、YOR157C、YOR185C、YOR197W、YOR259C、YOR261C、YOR273C、YOR288C、YOR332W、YOR336W、YOR347C、YPL017C、YPL087W、YPL106C、YPL109C、YPL149W、YPL154C、YPL196W、YPL206C、YPL222W、YPR023C、YPR024W、YPR026W、YPR067W、YPR103W、YPR108W、YPR151C、YAL012W、YBR029C、YBR222C、YCL009C、YCL027W、YCL064C、YCR098C、YDL222C、YDR055W、YDR077W、YDR502C、YEL001C、YEL042W、YER026C、YER106W、YGR136W、YGR138C、YHR137W、YHR142W、YIL023C、YIL153W、YJL073W、YJR004C、YJR054W、YKL039W、YKL086W、YKL163W、YKR091W、YLR109W、YLR194C、YLR250W、YMR095C、YMR189W、YNL106C、YNL169C、YNL322C、YOR181W、YOR198C、YOR208W、YOR247W、YPL089C、YAL038W、YAL053W、YBR023C、YBR214W、YBR295W、YCR048W、YDL072C、YDL204W、YDR085C、YDR098C、YDR259C、YDR380W、YDR388W、YDR391C、YDR432W、YDR481C、YDR510W、YER069W、YGL022W、YGL126W、YGL209W、YGL255W、YGR189C、YGR282C、YHL035C、YHR030C、YIL022W、YIL024C、YIL117C、YIL123W、YIL140W、YIL154C、YJL088W、YJL108C、YJL149W、YJL159W、YJL186W、YJR148W、YKL096W、YLR180W、YLR273C、YLR300W、YLR307W、YLR378C、YLR391W、YMR094W、YMR104C、YMR276W、YMR296C、YNL190W、YNL208W、YNL300W、YNR064C、YOL013C、YOL058W、YOR248W、YOR355W、YPL052W、YPL163C、YPR079W、YAR028W、YBR146W、YBR183W、YCL038C、YCR071C、YDL008W、YDR019C、YDR031W、YDR115W、YDR486C、YER038C、YER130C、YFL054C、YGL136C、YGR146C、YGR207C、YHL040C、YIL167W、YJL020C、YKR039W、YLR031W、YLR205C、YMR072W、YMR140W、YMR173W、YMR195W、YMR226C、YNL037C、YNR002C、YOL143C、YOR136W、YOR215C、YOR382W、YOR383C、YPL054W、YPL271W、YPR127W、YAL044C、YAL054C、YAR010C、YAR027W、YAR071W、YBL001C、YBL043W、YBL057C、YBR014C、YBR024W、YBR035C、YBR068C、YBR111C、YBR116C、YBR147W、YBR168W、YBR246W、YBR273C、YCR004C、YCR021C、YCR037C、YCR088W、YDL022W、YDL128W、YDL238C、YDR003W、YDR009W、YDR033W、YDR084C、YDR104C、YDR270W、YDR315C、YDR340W、YDR357C、YDR358W、YDR396W、YDR405W、YDR410C、YDR434W、YDR482C、YDR487C、YDR520C、YDR534C、YDR539W、YEL011W、YEL065W、YEL066W、YER039C、YER044C、YER067W、YER080W、YER107C、YFL020C、YFL028C、YFL043C、YFR015C、YGL001C、YGL008C、YGL068W、YGL073W、YGL104C、YGL113W、YGL154C、YGL167C、YGL229C、YGL242C、YGL249W、YGL253W、YGR052W、YGR060W、YGR065C、YGR106C、YGR111W、YGR220C、YGR257C、YHL023C、YHL048W、YHR004C、YHR037W、YHR071W、YHR092C、YHR190W、YIL007C、YIL033C、YIL070C、YIL088C、YIL111W、YIR002C、YIR016W、YIR035C、YIR043C、YJL012C、YJL083W、YJL089W、YJL116C、YJL131C、YJL132W、YJL196C、YJR061W、YJR086W、YJR142W、YJR161C、YKL008C、YKL013C、YKL041W、YKL067W、YKL138C、YKL139W、YKL150W、YKL175W、YKR006C、YKR014C、YKR070W、YLL023C、YLR023C、YLR093C、YLR118C、YLR142W、YLR225C、YLR241W、YLR251W、YLR252W、YLR270W、YML030W、YML110C、YMR021C、YMR027W、YMR148W、YMR181C、YMR262W、YMR272C、YMR298W、YNL011C、YNL130C、YNL214W、YNL259C、YOL129W、YOR042W、YOR052C、YOR137C、YOR149C、YOR165W、YOR270C、YOR285W、YOR367W、YPL018W、YPL156C、YPL186C、YPL203W、YPL216W、YPL255W、YPR006C、YPR073C、YPR098C、YBR050C、YBR145W、YBR299W、YDR518W、YEL020C、YFL062W、YGL039W、YGL134W、YJL217W、YJR159W、YLR126C、YNL249C、YNL284C、YNL336W、YOL157C、YOR344C、YOR381W、YPL265W、YPR124W、YBR074W、YBR109C、YBR126C、YBR201W、YCR005C、YDL248W、YDR041W、YDR105C、YDR268W、YDR452W、YEL075C、YER046W、YER050C、YER136W、YER159C、YGL250W、YGR019W、YGR042W、YGR053C、YGR066C、YGR247W、YGR255C、YGR295C、YHL044W、YHR145C、YIL058W、YIL065C、YIL083C、YIL098C、YIL172C、YJL030W、YJL185C、YJL213W、YJR029W、YJR099W、YJR122W、YJR125C、YKL190W、YKR020W、YLL025W、YLL051C、YLR043C、YLR090W、YLR100W、YLR108C、YLR290C、YML068W、YMR051C、YMR139W、YMR178W、YMR193W、YNL015W、YNL079C、YNL122C、YNL223W、YNL285W、YNL293W、YNR007C、YNR035C、YNR061C、YOL016C、YOL104C、YOR220W、YOR221C、YOR374W、YPL123C、YPR077C、YPR107C、YPR147C、YBR093C、YBR196C、YEL041W、YEL047C、YER023W、YER119C、YFL055W、YGR209C、YIL124W、YKL187C、YLL055W、YMR318C、YOL152W、YAL007C、YBR067C、YBR115C、YBR285W、YBR292C、YDL043C、YDL123W、YDL131W、YDL168W、YDL212W、YDR056C、YDR132C、YDR154C、YDR183W、YDR216W、YDR253C、YDR295C、YDR494W、YDR513W、YEL072W、YER045C、YER061C、YER181C、YFL052W、YFL058W、YFR030W、YGL089C、YGL096W、YGL114W、YGL193C、YGL202W、YGL204C、YGL259W、YGR006W、YGR070W、YGR088W、YHL034C、YHL036W、YHR048W、YHR104W、YHR163W、YIL060W、YIL136W、YIR024C、YJL036W、YJL045W、YJL060W、YJL101C、YJL155C、YJR085C、YJR109C、YJR156C、YKL070W、YKL161C、YKL221W、YKR071C、YLL009C、YLL050C、YLR092W、YLR145W、YLR156W、YLR163C、YLR220W、YLR280C、YLR311C、YLR390W、YML116W、YMR034C、YMR038C、YMR081C、YMR250W、YNL240C、YNL260C、YNL277W、YNR074C、YOL044W、YOL084W、YOL147C、YOL159C、YOR184W、YOR228C、YOR255W、YPL223C、YPR160W、YDL182W、YBR047W、YBR054W、YBR291C、YDR069C、YER124C、YER131W、Y・・・
IPC (9):
C12N 15/09 ZNA ,  C12Q 1/02 ,  C12Q 1/68 ,  G01N 27/447 ,  G01N 33/483 ,  G01N 33/53 ,  G01N 33/58 ,  G01N 33/68 ,  G01N 37/00 102
FI (9):
C12Q 1/02 ,  C12Q 1/68 A ,  G01N 33/483 F ,  G01N 33/53 M ,  G01N 33/58 A ,  G01N 33/68 ,  G01N 37/00 102 ,  C12N 15/00 ZNA A ,  G01N 27/26 325 C
F-Term (42):
2G045BA11 ,  2G045BA13 ,  2G045BB20 ,  2G045CB21 ,  2G045DA12 ,  2G045DA13 ,  2G045DA14 ,  2G045DA36 ,  2G045FB02 ,  2G045FB05 ,  2G045FB07 ,  2G045FB16 ,  2G045HA16 ,  4B024AA11 ,  4B024CA04 ,  4B024CA09 ,  4B024DA12 ,  4B024EA04 ,  4B024GA11 ,  4B024GA19 ,  4B024HA12 ,  4B024HA19 ,  4B063QA01 ,  4B063QA12 ,  4B063QA17 ,  4B063QA18 ,  4B063QQ20 ,  4B063QQ53 ,  4B063QR32 ,  4B063QR38 ,  4B063QR55 ,  4B063QR59 ,  4B063QR69 ,  4B063QR76 ,  4B063QR80 ,  4B063QR82 ,  4B063QS24 ,  4B063QS25 ,  4B063QS28 ,  4B063QS34 ,  4B063QS39 ,  4B063QX02
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