Pat
J-GLOBAL ID:200903096551459740
ラクダ科動物のVHHドメインの安定化
Inventor:
Applicant, Patent owner:
Gazette classification:公開公報
Application number (International application number):2007058019
Publication number (International publication number):2008212125
Application date: Mar. 08, 2007
Publication date: Sep. 18, 2008
Summary:
【課題】ラクダ科動物抗体の保存安定性、熱安定性を高める。【解決手段】ラクダ科動物抗体VHHドメインに2個のシステイン残基を導入し、これらシステイン残基間にS-S結合を導入してなる、安定化ラクダ科動物抗体。【選択図】図1
Claim (excerpt):
ラクダ科動物抗体VHHドメインに2個のシステイン残基を導入し、これらシステイン残基間にS-S結合を導入してなる、安定化ラクダ科動物抗体。
IPC (4):
C12N 15/09
, C07K 16/00
, C12N 1/19
, C12P 21/02
FI (4):
C12N15/00 A
, C07K16/00
, C12N1/19
, C12P21/02 C
F-Term (40):
4B024AA11
, 4B024BA61
, 4B024CA04
, 4B024CA05
, 4B024CA06
, 4B024CA09
, 4B024CA10
, 4B024CA11
, 4B024DA12
, 4B024EA04
, 4B024FA02
, 4B024FA10
, 4B024GA11
, 4B024GA19
, 4B024HA03
, 4B024HA08
, 4B024HA09
, 4B024HA14
, 4B064AG26
, 4B064CA06
, 4B064CA19
, 4B064CC24
, 4B064DA13
, 4B065AA72X
, 4B065AA90Y
, 4B065AB01
, 4B065AC14
, 4B065BA02
, 4B065BA24
, 4B065CA24
, 4B065CA46
, 4H045AA10
, 4H045AA20
, 4H045BA10
, 4H045BA32
, 4H045CA40
, 4H045DA75
, 4H045EA50
, 4H045FA72
, 4H045FA74
Article cited by the Patent:
Cited by examiner (1)
-
Protein Sci., 1993, 2(10), pp.1551-1558
Return to Previous Page