J-GLOBAL ID:200904008807868519  Research Project code:0150000210 Update date:Jan. 17, 2002

Analysis of the structure, expression and function of the genes and proteins involved in tumor suppression.

Study period:2000 - 2003
Organization (1):
Investigating Researcher (1):
Research overview:
This project aims to elucidate the molecular mechanisms of carcinogenesis and tumor suppression through structural and functional analyses of the human genome. To this end, novel tumor suppressor genes involved in human lung, prostate, pancreas, liver or brain tumors are being mapped, identified and characterized. The genetic basis of cancer susceptibility of individuals is also being investigated. Our ultimate goal is to identify and characterize the molecular targets for prevention, diagnosis and treatment of human cancer.
Keywords (4):
tumor suppressor gene ,  lung cancer ,  chromosome 11 ,  allele specific expression
Research program: Health and Labour Sciences Research Grants
Ministry with control over the research :
Ministry of Health, Labour and Welfare
Organization with control over the research:
National Cancer Center, Research Institute
Research budget: 2001: \15,000,000

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