J-GLOBAL ID:200904011055133442  Research Project code:0250008929 Update date:Nov. 24, 2004

Neural mechanism of the eye movement control

Study period:1998 - 0
Organization (1):
Investigating Researcher (1):
Research overview:
Cholinergic signaling and sensory-motor control systems. The cholinergic pedunculopontine tegmental nucleus (PPTN) is one of the major ascending arousal systems in the brain stem, and is linked to motor and limbic systems. We hypothesize that PPTN is related to integrative control of movement in behaving animals, and present a new model of the PPTN's involvement in the control of arousal, attention and reinforcement aspects of motor behavior, with a focus on the control of saccades. We are investigating the relationship between the task performance and activity of PPTN neurons during visually guided saccade task and the effects of reward schedule on them.
Keywords (1):
saccade learning primates
Research program: -
Research budget: 2004: \2,900,000

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