Proj
J-GLOBAL ID:200904021436964028  Research Project code:9800044089 Update date:Jan. 12, 1998

Quantitative analysis of cytokine mRNA expression in peripheral blood mononuclear cells during operation and severe shock

周術期および重症ショック時の末梢血単核球のサイトカインmRNA発現の定量的解析
Study period:1997 - 1998
Organization (1):
Investigating Researcher (1):
Research overview:
Recently we have established the quantitative assay for measuring cytokine mRNA expression in peripheral blood mononuclear cells. By using this method, we have the following plans: 1) to clarify the cytokine networks during operation and severe shock, such as hemorrhagic shock or septic shock, and 2) to clarify whether the drugs, such as anesthetic agents, steroid, and protease inhibitor, can inhibit cytokine production. These studies would provide useful information for the control of cytokine production during operation and severe shock.
Keywords (5):
cytokine ,  mRNA ,  monocyte ,  quantitative ,  polymerase
Research program: Ordinary Research
Research budget: 1997: \1,600,000

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