J-GLOBAL ID:200904036193604254  Research Project code:9800028183 Update date:Dec. 05, 2002

Investigation of tumor promotion by the okadaic acid class compounds

Study period:1994 - 2001
Organization (1):
Investigating Researcher (1):
Research overview:
Okadaic acid, which is an inhibitor of protein phosphatases 1 and 2A, provides a general biochemical mechanism of tumor promotion applicable to various organs. Stimulation of protein phosphorylation and gene expession by these compounds is now under investigation.
Keywords (5):
tumor promoter ,  protein ,  phosphorylation ,  gene ,  expression
Research program: Ordinary Research

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