J-GLOBAL ID:200904054986153820  Research Project code:9800001773 Update date:Jan. 21, 1997

Mechanism of liver specific gene expression

Study period:1975 - 1995
Organization (1):
Investigating Researcher (1):
Research overview:
Mechanisms of hormonal regulation of enzyme inductions in liver cells are studied on gene level by using their cDNAs. T ranscripition factors for liver-specific genes during differentiation are studing. A member of GATA-binding protein is possible to inhibit the expression of some liver-specific genes in fetus.
Keywords (10):
liver ,  cultured ,  amino ,  insulin ,  glucagon ,  glucocorticoid ,  cDNA ,  transcription ,  enzyme ,  differentiation(biology)
Research program: Ordinary Research
Research budget: 1995: \2,000,000

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