J-GLOBAL ID:200904094537658014  Research Project code:9800015558 Update date:Dec. 20, 2002

Molecular mechanisms of multi-stage carcinogenesis in human epithelial cells

Study period:1986 - 0
Organization (1):
Investigating Researcher (3):
Research overview:
Establishing a number of human epithelial cell lines transformed by DNA tumor viruses including HPV16, SV40, and hTERT progressive changes of cellular phenotypes toward malignancy have been correlated with uncontrolled cell proliferation, immortalization and full transformation. By using these unique system, molecular events associated with their progressive transformation of human cells are studied.
Keywords (8):
epithelial cells ,  molecular cell Biology ,  DNA tumor viruses ,  transformation(genetics) ,  immortalization ,  cancer ,  不死化 ,  癌
Research program: Ordinary Research

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